ASZ1 Antibody, FITC conjugated (PACO39224)
- SKU:
- PACO39224
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ASZ1 Antibody, FITC conjugated (PACO39224) |
抗体コード: | PACO39224 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation. |
シノニム: | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Ankyrin-like protein 1) (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein), ASZ1, ALP1 ANKL1 C7orf7 GASZ |
UniProt Protein Function: | ASZ1: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 7q31.2 Cellular Component: cytoplasm Molecular Function:signal transducer activity Biological Process: DNA methylation during gametogenesis; multicellular organismal development; RNA-mediated gene silencing; spermatogenesis; gene expression; male meiosis; signal transduction; cell differentiation |
UniProt Code: | Q8WWH4 |
NCBI GenInfo Identifier: | 18640738 |
NCBI Gene ID: | 136991 |
NCBI Accession: | NP_570124.1 |
UniProt Secondary Accession: | Q8WWH4,A0AV27, A4D0V0, |
UniProt Related Accession: | Q8WWH4 |
Molecular Weight: | 53,458 Da |
NCBI Full Name: | ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 isoform 1 |
NCBI Synonym Full Names: | ankyrin repeat, SAM and basic leucine zipper domain containing 1 |
NCBI Official Symbol: | ASZ1 |
NCBI Official Synonym Symbols: | ALP1; GASZ; Orf3; ANKL1; C7orf7; CT1.19 |
NCBI Protein Information: | ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; ankyrin-like protein 1; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein |
UniProt Protein Name: | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 |
UniProt Synonym Protein Names: | Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein |
Protein Family: | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein |
UniProt Gene Name: | ASZ1 |
UniProt Entry Name: | ASZ1_HUMAN |