AOC3 Antibody, FITC conjugated (PACO54496)
- SKU:
- PACO54496
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | AOC3 Antibody, FITC conjugated (PACO54496) |
抗体コード: | PACO54496 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Membrane primary amine oxidase protein (27-259AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis. |
シノニム: | Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (HPAO) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1), AOC3, VAP1 |
UniProt Protein Function: | AOC3: Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin- independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. Belongs to the copper/topaquinone oxidase family. |
UniProt Protein Details: | Protein type:Cell adhesion; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Other Amino Acids Metabolism - beta-alanine; Membrane protein, integral; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; EC 1.4.3.21 Chromosomal Location of Human Ortholog: 17q21 Cellular Component: cell surface; microvillus; cytoplasm; plasma membrane; integral to membrane Molecular Function:amine oxidase activity; protein binding; protein homodimerization activity; copper ion binding; protein heterodimerization activity; cation channel activity; calcium ion binding; quinone binding Biological Process: response to antibiotic; amine metabolic process; cell adhesion; inflammatory response; cation transport |
NCBI Summary: | This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
UniProt Code: | Q16853 |
NCBI GenInfo Identifier: | 2501336 |
NCBI Gene ID: | 8639 |
NCBI Accession: | Q16853.3 |
UniProt Related Accession: | Q16853 |
Molecular Weight: | Molecular Mass: 108.5kDaActual Protein Molecular Mass: 120kDa |
NCBI Full Name: | Membrane primary amine oxidase |
NCBI Synonym Full Names: | amine oxidase copper containing 3 |
NCBI Official Symbol: | AOC3 |
NCBI Official Synonym Symbols: | HPAO; SSAO; VAP1; VAP-1 |
NCBI Protein Information: | membrane primary amine oxidase |
UniProt Protein Name: | Membrane primary amine oxidase |
UniProt Synonym Protein Names: | Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1 |
Protein Family: | Membrane primary amine oxidase |
UniProt Gene Name: | AOC3 |
UniProt Entry Name: | AOC3_HUMAN |