Anti-ZP1 Antibody (CAB10776)
- SKU:
- CAB10776
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-ZP1 Antibody |
抗体コード: | CAB10776 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human ZP1 (NP_997224.2). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | OVCAR8, OVCAR3, SKOV3, NCI-H460, A-549, Mouse lung, Rat ovary, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human ZP1 (NP_997224.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AGDQ LIYE NWLV SGIH IQKG PQGS ITRD STFQ LHVR CVFN ASDF LPIQ ASIF PPPS PAPM TQPG PLRL ELRI AKDE TFSS YYGE DDYP IVRL LREP VHVE VRLL QRTD PNLV LLLH QCWG APSA NPFQ QPQW PILS DGCP FKGD SYRT QMVA LDGA TPFQ SHYQ RFTV ATFA LLDS GSQR ALRG LVYL FCST SACH TSGL ETCS TACS TGTT RQRR SSGH RNDT ARPQ DIVS SPGP VGFE DSYG QEPT LGPT DSNG NSSL RPLL WAVL LLP |
遺伝子ID: | 22917 |
Uniprot: | P60852 |
セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein, extracellular matrix, extracellular space |
計算された分子量: | 70kDa |
観察された分子量: | 70kDa |
同義語: | ZP1, HEL163, OOMD, OOMD1 |
バックグラウンド: | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. |
UniProt Protein Function: | ZP1: The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. Belongs to the ZP domain family. ZPB subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q12.2 Cellular Component: extracellular region Biological Process: binding of sperm to zona pellucida Disease: Oocyte Maturation Defect |
NCBI Summary: | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014] |
UniProt Code: | P60852 |
NCBI GenInfo Identifier: | 46397079 |
NCBI Gene ID: | 22917 |
NCBI Accession: | P60852.1 |
UniProt Related Accession: | P60852 |
Molecular Weight: | 70kDa |
NCBI Full Name: | Zona pellucida sperm-binding protein 1 |
NCBI Synonym Full Names: | zona pellucida glycoprotein 1 |
NCBI Official Symbol: | ZP1 |
NCBI Official Synonym Symbols: | OOMD; OOMD1; HEL163 |
NCBI Protein Information: | zona pellucida sperm-binding protein 1 |
UniProt Protein Name: | Zona pellucida sperm-binding protein 1 |
UniProt Synonym Protein Names: | Zona pellucida glycoprotein 1; Zp-1 |
Protein Family: | Zona pellucida sperm-binding protein |
UniProt Gene Name: | ZP1 |
View AllClose