Anti-ZMIZ2 Antibody (CAB17301)
- SKU:
- CAB17301
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-ZMIZ2 Antibody |
抗体コード: | CAB17301 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human ZMIZ2 (NP_001287888). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-87MG, Jurkat, HeLa, 293T, mouse brain, rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human ZMIZ2 (NP_001287888). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MNSM NPMK PALP PAPH GDGS FAYE SVPW QQSA TQPA GSLS VVTT VWGV GNAT QSQC LGQQ AFAE GGAN KGYV QQGV YSRG GYPG APGF TTGY AGGP GGLG LPSH AARP ST |
遺伝子ID: | 83637 |
Uniprot: | Q8NF64 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 115kDa |
同義語: | ZMIZ2, NET27, TRAFIP20, ZIMP7, hZIMP7 |
バックグラウンド: | ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]). |
UniProt Protein Function: | ZIMP7: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 7p13 Cellular Component: nucleoplasm; mitochondrion; nuclear replication fork; nucleus Molecular Function:protein binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] |
UniProt Code: | Q8NF64 |
NCBI GenInfo Identifier: | 54607108 |
NCBI Gene ID: | 83637 |
NCBI Accession: | NP_113637.3 |
UniProt Secondary Accession: | Q8NF64,O94790, Q0VGB4, Q659A8, Q6JKL5, Q8WTX8, Q96Q01 Q9BQH7, A4D2K7, D3DVL1, |
UniProt Related Accession: | Q8NF64 |
Molecular Weight: | 96,537 Da |
NCBI Full Name: | zinc finger MIZ domain-containing protein 2 isoform 1 |
NCBI Synonym Full Names: | zinc finger, MIZ-type containing 2 |
NCBI Official Symbol: | ZMIZ2 |
NCBI Official Synonym Symbols: | NET27; ZIMP7; hZIMP7; TRAFIP20 |
NCBI Protein Information: | zinc finger MIZ domain-containing protein 2; PIAS-like protein Zimp7 |
UniProt Protein Name: | Zinc finger MIZ domain-containing protein 2 |
UniProt Synonym Protein Names: | PIAS-like protein Zimp7 |
Protein Family: | Zinc finger MIZ domain-containing protein |
UniProt Gene Name: | ZMIZ2 |
UniProt Entry Name: | ZMIZ2_HUMAN |
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