Anti-Zip12 Antibody (CAB16006)
- SKU:
- CAB16006
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-Zip12 Antibody |
抗体コード: | CAB16006 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, mouse brain, mouse eye, mouse lung, rat brain |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC39A12 (NP_001138667.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MCFR TKLS VSWV PLFL LLSR VFST ETDK PSAQ DSRS RGSS GQPA DLLQ VLSA GDHP PHNH SRSL IKTL LEKT GCPR RRNG MQGD CNLC FEPD ALLL IAGG |
遺伝子ID: | 221074 |
Uniprot: | Q504Y0 |
セルラーロケーション: | |
計算された分子量: | 45kDa/61kDa/72kDa/76kDa |
観察された分子量: | 77kDa |
同義語: | SLC39A12, LZT-Hs8, ZIP-12, bA570F3.1, Zip12 |
バックグラウンド: | Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]). |
UniProt Protein Function: | SLC39A12: Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. Belongs to the ZIP transporter (TC 2.A.5) family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 10p12.33 Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; vesicle Molecular Function:zinc ion transmembrane transporter activity Biological Process: signal transduction; regulation of microtubule polymerization |
NCBI Summary: | Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008] |
UniProt Code: | Q504Y0 |
NCBI GenInfo Identifier: | 223633939 |
NCBI Gene ID: | 221074 |
NCBI Accession: | NP_001138667 |
UniProt Related Accession: | Q504Y0 |
Molecular Weight: | 45kDa; 61kDa; 72kDa; 76kDa |
NCBI Full Name: | zinc transporter ZIP12 isoform 1 |
NCBI Synonym Full Names: | solute carrier family 39 member 12 |
NCBI Official Symbol: | SLC39A12 |
NCBI Official Synonym Symbols: | ZIP-12; LZT-Hs8; bA570F3.1 |
NCBI Protein Information: | zinc transporter ZIP12 |
UniProt Protein Name: | Zinc transporter ZIP12 |
UniProt Synonym Protein Names: | LIV-1 subfamily of ZIP zinc transporter 8; LZT-Hs8; Solute carrier family 39 member 12; Zrt- and Irt-like protein 12; ZIP-12 |
Protein Family: | Probable zinc transporter |
UniProt Gene Name: | SLC39A12 |
UniProt Entry Name: | S39AC_HUMAN |
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