Anti-ZFAND5 Antibody (CAB13185)
- SKU:
- CAB13185
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-ZFAND5 Antibody |
抗体コード: | CAB13185 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ZFAND5 (NP_001095890.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:1000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse eye |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ZFAND5 (NP_001095890.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RQQN SGRM SPMG TASG SNSP TSDS ASVQ RADT SLNN CEGA AGST SEKS RNVP VAAL PVTQ QMTE MSIS REDK ITTP KTEV SEPV VTQP SPSV SQPS TSQS EEKA PELP KPK |
遺伝子ID: | 7763 |
Uniprot: | O76080 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 23kDa |
観察された分子量: | 23kDa |
同義語: | ZFAND5, ZA20D2, ZFAND5A, ZNF216 |
バックグラウンド: |
UniProt Protein Function: | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
UniProt Code: | O76080 |
NCBI GenInfo Identifier: | 156231047 |
NCBI Gene ID: | 7763 |
NCBI Accession: | NP_001095890.1 |
UniProt Secondary Accession: | O76080,A8K484, |
UniProt Related Accession: | O76080 |
Molecular Weight: | 23,132 Da |
NCBI Full Name: | AN1-type zinc finger protein 5 |
NCBI Synonym Full Names: | zinc finger AN1-type containing 5 |
NCBI Official Symbol: | ZFAND5 |
NCBI Official Synonym Symbols: | ZA20D2; ZNF216; ZFAND5A |
NCBI Protein Information: | AN1-type zinc finger protein 5 |
UniProt Protein Name: | AN1-type zinc finger protein 5 |
UniProt Synonym Protein Names: | Zinc finger A20 domain-containing protein 2; Zinc finger protein 216 |
Protein Family: | AN1-type zinc finger protein |
UniProt Gene Name: | ZFAND5 |
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