Anti-WIPI2 Antibody (CAB7537)
- SKU:
- CAB7537
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
抗体名: | Anti-WIPI2 Antibody |
抗体コード: | CAB7537 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 187-436 of human WIPI2 (NP_057087.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Jurkat, BT-474 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 187-436 of human WIPI2 (NP_057087.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LAAL AFDA SGTK LATA SEKG TVIR VFSI PEGQ KLFE FRRG VKRC VSIC SLAF SMDG MFLS ASSN TETV HIFK LETV KEKP PEEP TTWT GYFG KVLM ASTS YLPS QVTE MFNQ GRAF ATVR LPFC GHKN ICSL ATIQ KIPR LLVG AADG YLYM YNLD PQEG GECA LMKQ HRLD GSLE TTNE ILDS ASHD CPLV TQTY GAAA GKGT YVPS SPTR LAYT DDLG AVGG ACLE DEAS ALRL DEDS EHPP MILR TD |
遺伝子ID: | 26100 |
Uniprot: | Q9Y4P8 |
セルラーロケーション: | Cytoplasmic side, Peripheral membrane protein, Preautophagosomal structure membrane |
計算された分子量: | 42kDa/46kDa/47kDa/48kDa/49kDa |
観察された分子量: | 48kDa |
同義語: | WIPI2, ATG18B, Atg21, CGI-50, WIPI-2 |
バックグラウンド: |
UniProt Protein Function: | Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P. |
NCBI Summary: | WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9Y4P8 |
NCBI GenInfo Identifier: | 74762063 |
NCBI Gene ID: | 26100 |
NCBI Accession: | Q9Y4P8.1 |
UniProt Secondary Accession: | Q9Y4P8,Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364, B3KNC2 |
UniProt Related Accession: | Q9Y4P8 |
Molecular Weight: | 49kDa |
NCBI Full Name: | WD repeat domain phosphoinositide-interacting protein 2 |
NCBI Synonym Full Names: | WD repeat domain, phosphoinositide interacting 2 |
NCBI Official Symbol: | WIPI2 |
NCBI Official Synonym Symbols: | Atg21; ATG18B; CGI-50; WIPI-2 |
NCBI Protein Information: | WD repeat domain phosphoinositide-interacting protein 2 |
UniProt Protein Name: | WD repeat domain phosphoinositide-interacting protein 2 |
UniProt Synonym Protein Names: | WIPI49-like protein 2 |
Protein Family: | WD repeat domain phosphoinositide-interacting protein |
UniProt Gene Name: | WIPI2 |
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