Anti-UQCRC2 Antibody (CAB4181)
- SKU:
- CAB4181
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-UQCRC2 Antibody |
抗体コード: | CAB4181 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IP |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 224-453 of human UQCRC2 (NP_003357.2). |
申し込み: | WB IHC IP |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, MCF7, HepG2, H460, Mouse kidney, Mouse brain, Mouse liver, Rat spinal cord, Rat testis, NCI-H460 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 224-453 of human UQCRC2 (NP_003357.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GVSH PVLK QVAE QFLN MRGG LGLS GAKA NYRG GEIR EQNG DSLV HAAF VAES AVAG SAEA NAFS VLQH VLGA GPHV KRGS NTTS HLHQ AVAK ATQQ PFDV SAFN ASYS DSGL FGIY TISQ ATAA GDVI KAAY NQVK TIAQ GNLS NTDV QAAK NKLK AGYL MSVE SSEC FLEE VGSQ ALVA GSYM PPST VLQQ IDSV ANAD IINA AKKF VSGQ KSMA ASGN LGHT PFVD EL |
遺伝子ID: | 7385 |
Uniprot: | P22695 |
セルラーロケーション: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein |
計算された分子量: | 48kDa |
観察された分子量: | 48kDa |
同義語: | UQCRC2, MC3DN5, QCR2, UQCR2 |
バックグラウンド: | The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. |
UniProt Protein Function: | UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily. |
UniProt Protein Details: | Protein type:EC 1.10.2.2; Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 16p12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5 |
NCBI Summary: | The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015] |
UniProt Code: | P22695 |
NCBI GenInfo Identifier: | 21903482 |
NCBI Gene ID: | 7385 |
NCBI Accession: | P22695.3 |
UniProt Secondary Accession: | P22695,Q9DB77, P32551, |
UniProt Related Accession: | P22695 |
Molecular Weight: | 48kDa |
NCBI Full Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase core protein 2 |
NCBI Official Symbol: | UQCRC2 |
NCBI Official Synonym Symbols: | QCR2; UQCR2; MC3DN5 |
NCBI Protein Information: | cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Protein Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
UniProt Synonym Protein Names: | Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2 |
UniProt Gene Name: | UQCRC2 |
UniProt Entry Name: | QCR2_HUMAN |
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