Anti-UBE2J2 Antibody (CAB7316)
- SKU:
- CAB7316
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-UBE2J2 Antibody |
抗体コード: | CAB7316 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, HeLa, 293T, Mouse testis, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSST SSKR APTT ATQR LKQD YLRI KKDP VPYI CAEP LPSN ILEW HYVV RGPE MTPY EGGY YHGK LIFP REFP FKPP SIYM ITPN GRFK CNTR LCLS ITDF HPDT WNPA WSVS TILT GLLS FMVE KGPT LGSI ETSD FTKR QLAV QSLA FNLK DKVF CELF PEVV EEIK QKQK AQDE LSSR PQTL PLPD VVPD GETH LVQN GIQL LNGH APGA VPNL AGLQ QANR HHGL LG |
遺伝子ID: | 118424 |
Uniprot: | Q8N2K1 |
セルラーロケーション: | Endoplasmic reticulum membrane, Single-pass type IV membrane protein |
計算された分子量: | 24kDa/28kDa/30kDa |
観察された分子量: | 29kDa |
同義語: | UBE2J2, NCUBE-2, NCUBE2, PRO2121 |
バックグラウンド: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. |
UniProt Protein Function: | UBE2J2: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ligase; Ubiquitin conjugating system; EC 6.3.2.19; Endoplasmic reticulum; Ubiquitin ligase; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.33 Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane Molecular Function:small conjugating protein ligase activity; ubiquitin protein ligase binding; ATP binding; ligase activity Biological Process: ER-associated protein catabolic process; protein polyubiquitination; response to unfolded protein |
NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8N2K1 |
NCBI GenInfo Identifier: | 251757431 |
NCBI Gene ID: | 118424 |
NCBI Accession: | Q8N2K1.3 |
UniProt Secondary Accession: | Q8N2K1,Q504T9, Q96N26, Q96T84, A8MYC7, |
UniProt Related Accession: | Q8N2K1 |
Molecular Weight: | 259 |
NCBI Full Name: | Ubiquitin-conjugating enzyme E2 J2 |
NCBI Synonym Full Names: | ubiquitin-conjugating enzyme E2, J2 |
NCBI Official Symbol: | UBE2J2 |
NCBI Official Synonym Symbols: | NCUBE2; NCUBE-2; PRO2121 |
NCBI Protein Information: | ubiquitin-conjugating enzyme E2 J2; yeast UBC6 homolog; ubiquitin conjugating enzyme 6; ubiquitin conjugating enzyme E2, J2; non-canonical ubiquitin-conjugating enzyme 2; ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast) |
UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 J2 |
UniProt Synonym Protein Names: | Non-canonical ubiquitin-conjugating enzyme 2; NCUBE-2 |
Protein Family: | Ubiquitin-conjugating enzyme |
UniProt Gene Name: | UBE2J2 |
UniProt Entry Name: | UB2J2_HUMAN |
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