Anti-UBE2G1 Antibody (CAB6997)
- SKU:
- CAB6997
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-UBE2G1 Antibody |
抗体コード: | CAB6997 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human UBE2G1 (NP_003333.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human UBE2G1 (NP_003333.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MTEL QSAL LLRR QLAE LNKN PVEG FSAG LIDD NDLY RWEV LIIG PPDT LYEG GVFK AHLT FPKD YPLR PPKM KFIT EIWH PNVD KNGD VCIS ILHE PGED KYGY EKPE ERWL PIHT VETI MISV ISML ADPN GDSP ANVD AAKE WRED RNGE FKRK VARC VRKS QETA FE |
遺伝子ID: | 7326 |
Uniprot: | P62253 |
セルラーロケーション: | |
計算された分子量: | 19kDa |
観察された分子量: | Refer to figures |
同義語: | UBE2G1, E217K, UBC7, UBE2G |
バックグラウンド: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. |
UniProt Protein Function: | UBE2G1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. Belongs to the ubiquitin-conjugating enzyme family. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ligase; Ubiquitin ligase; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 17p13.2 Cellular Component: cytoplasm Molecular Function:small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity Biological Process: ubiquitin-dependent protein catabolic process; cellular protein catabolic process |
NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008] |
UniProt Code: | P62253 |
NCBI GenInfo Identifier: | 51338681 |
NCBI Gene ID: | 7326 |
NCBI Accession: | P62253.3 |
UniProt Secondary Accession: | P62253,Q99462, B2R7P2, D3DTK0, |
UniProt Related Accession: | P62253 |
Molecular Weight: | 170 |
NCBI Full Name: | Ubiquitin-conjugating enzyme E2 G1 |
NCBI Synonym Full Names: | ubiquitin-conjugating enzyme E2G 1 |
NCBI Official Symbol: | UBE2G1 |
NCBI Official Synonym Symbols: | UBC7; E217K; UBE2G |
NCBI Protein Information: | ubiquitin-conjugating enzyme E2 G1; ubiquitin-protein ligase G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7) |
UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 G1 |
UniProt Synonym Protein Names: | E217K; UBC7; Ubiquitin carrier protein G1; Ubiquitin-protein ligase G1Ubiquitin-conjugating enzyme E2 G1, N-terminally processed |
Protein Family: | Ubiquitin-conjugating enzyme |
UniProt Gene Name: | UBE2G1 |
UniProt Entry Name: | UB2G1_HUMAN |
Immunofluorescence analysis of U2OS cells using UBE2G1 antibody (CAB6997). Blue: DAPI for nuclear staining. |
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