Anti-TXNDC12 Antibody (CAB14403)
- SKU:
- CAB14403
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-TXNDC12 Antibody |
抗体コード: | CAB14403 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 93-172 of human TXNDC12 (NP_056997.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, 293T, HepG2, Mouse brain, Mouse heart, Mouse kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 93-172 of human TXNDC12 (NP_056997.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NLED EEEP KDED FSPD GGYI PRIL FLDP SGKV HPEI INEN GNPS YKYF YVSA EQVV QGMK EAQE RLTG DAFR KKHL EDEL |
遺伝子ID: | 51060 |
Uniprot: | O95881 |
セルラーロケーション: | Endoplasmic reticulum lumen |
計算された分子量: | 19kDa |
観察された分子量: | 19kDa |
同義語: | TXNDC12, AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19 |
バックグラウンド: | This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. |
UniProt Protein Function: | TXNDC12: Possesses significant protein thiol-disulfide oxidase activity. |
UniProt Protein Details: | Protein type:Secreted; Other Amino Acids Metabolism - glutathione; Oxidoreductase; Secreted, signal peptide; EC 1.8.4.2 Chromosomal Location of Human Ortholog: 1p32.3 Cellular Component: endoplasmic reticulum lumen Molecular Function:peptide disulfide oxidoreductase activity; protein binding |
NCBI Summary: | This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012] |
UniProt Code: | O95881 |
NCBI GenInfo Identifier: | 29839456 |
NCBI Gene ID: | 51060 |
NCBI Accession: | O95881.1 |
UniProt Secondary Accession: | O95881,Q5T1T4, Q96H50, B3KQS0, |
UniProt Related Accession: | O95881 |
Molecular Weight: | 19,206 Da |
NCBI Full Name: | Thioredoxin domain-containing protein 12 |
NCBI Synonym Full Names: | thioredoxin domain containing 12 |
NCBI Official Symbol: | TXNDC12 |
NCBI Official Synonym Symbols: | AG1; AGR1; ERP16; ERP18; ERP19; TLP19; hAG-1; PDIA16; hTLP19 |
NCBI Protein Information: | thioredoxin domain-containing protein 12 |
UniProt Protein Name: | Thioredoxin domain-containing protein 12 |
UniProt Synonym Protein Names: | Endoplasmic reticulum resident protein 18; ER protein 18; ERp18; Endoplasmic reticulum resident protein 19; ER protein 19; ERp19; Thioredoxin-like protein p19; hTLP19 |
Protein Family: | Thioredoxin domain-containing protein |
UniProt Gene Name: | TXNDC12 |
UniProt Entry Name: | TXD12_HUMAN |
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