Anti-TRIM54 Antibody (CAB13111)
- SKU:
- CAB13111
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-TRIM54 Antibody |
抗体コード: | CAB13111 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-358 of human TRIM54 (NP_912730.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | A-549, Mouse heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 179-358 of human TRIM54 (NP_912730.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | AMLV AGND RVQA VITQ MEEV CQTI EDNS RRQK QLLN QRFE SLCA VLEE RKGE LLQA LARE QEEK LQRV RGLI RQYG DHLE ASSK LVES AIQS MEEP QMAL YLQQ AKEL INKV GAMS KVEL AGRP EPGY ESME QFTV RVEH VAEM LRTI DFQP GASG EEEE VAPD GEEG SAGP EEER PDGP |
遺伝子ID: | 57159 |
Uniprot: | Q9BYV2 |
セルラーロケーション: | Cytoplasm, Z line, cytoskeleton, myofibril, sarcomere |
計算された分子量: | 40kDa/44kDa |
観察された分子量: | 40kDa |
同義語: | TRIM54, MURF, MURF-3, RNF30, muRF3 |
バックグラウンド: | The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
UniProt Protein Function: | TRIM54: May bind and stabilize microtubules during myotubes formation. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ligase; Ubiquitin ligase; EC 6.3.2.-; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: microtubule; microtubule associated complex; Z disc Molecular Function:signal transducer activity; zinc ion binding; microtubule binding Biological Process: negative regulation of microtubule depolymerization; multicellular organismal development; signal transduction; cell differentiation; microtubule-based process |
NCBI Summary: | The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BYV2 |
NCBI GenInfo Identifier: | 209572715 |
NCBI Gene ID: | 57159 |
NCBI Accession: | Q9BYV2.3 |
UniProt Secondary Accession: | Q9BYV2,Q53SY4, Q9BYV3, A5D8T7, |
UniProt Related Accession: | Q9BYV2 |
Molecular Weight: | 358 |
NCBI Full Name: | Tripartite motif-containing protein 54 |
NCBI Synonym Full Names: | tripartite motif containing 54 |
NCBI Official Symbol: | TRIM54 |
NCBI Official Synonym Symbols: | MURF; RNF30; muRF3; MURF-3 |
NCBI Protein Information: | tripartite motif-containing protein 54; ring finger protein 30; tripartite motif-containing 54; muscle-specific RING finger protein 3; muscle-specific RING-finger protein 3 |
UniProt Protein Name: | Tripartite motif-containing protein 54 |
UniProt Synonym Protein Names: | Muscle-specific RING finger protein; MuRF; Muscle-specific RING finger protein 3; MuRF-3; MuRF3; RING finger protein 30 |
Protein Family: | Tripartite motif-containing protein |
UniProt Gene Name: | TRIM54 |
UniProt Entry Name: | TRI54_HUMAN |
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