Anti-TRIM38 Antibody (CAB2600)
- SKU:
- CAB2600
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-TRIM38 Antibody |
抗体コード: | CAB2600 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 266-465 of human TRIM38 (NP_006346.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:1000 |
反応性: | Human |
ポジティブサンプル: | A-549, HeLa, HT-29 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 266-465 of human TRIM38 (NP_006346.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VSLE LHTM CNVS KLYF DVKK MLRS HQVS VTLD PDTA HHEL ILSE DRRQ VTRG YTQE NQDT SSRR FTAF PCVL GCEG FTSG RRYF EVDV GEGT GWDL GVCM ENVQ RGTG MKQE PQSG FWTL RLCK KKGY VALT SPPT SLHL HEQP LLVG IFLD YEAG VVSF YNGN TGCH IFTF PKAS FSDT LRPY FQVY QYSP LFLP PPGD |
遺伝子ID: | 10475 |
Uniprot: | O00635 |
セルラーロケーション: | |
計算された分子量: | 53kDa |
観察された分子量: | 53kDa |
同義語: | TRIM38, RNF15, RORET |
バックグラウンド: | This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. |
UniProt Protein Function: | TRIM38: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470} |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol Molecular Function:protein binding; signal transducer activity Biological Process: activation of NF-kappaB transcription factor; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; positive regulation of virion penetration into host cell |
NCBI Summary: | This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012] |
UniProt Code: | O00635 |
NCBI GenInfo Identifier: | 21362879 |
NCBI Gene ID: | 10475 |
NCBI Accession: | O00635.1 |
UniProt Secondary Accession: | O00635,B2R862, |
UniProt Related Accession: | O00635 |
Molecular Weight: | 53,416 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM38 |
NCBI Synonym Full Names: | tripartite motif containing 38 |
NCBI Official Symbol: | TRIM38 |
NCBI Official Synonym Symbols: | RNF15; RORET |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM38 |
UniProt Synonym Protein Names: | RING finger protein 15; Tripartite motif-containing protein 38; Zinc finger protein RoRet |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM38 |
UniProt Entry Name: | TRI38_HUMAN |
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