Anti-TREM1 Antibody (CAB0292)
- SKU:
- CAB0292
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-TREM1 Antibody |
抗体コード: | CAB0292 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-130 of human TREM1 (NP_061113.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
反応性: | Human, Rat |
ポジティブサンプル: | HL-60 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-130 of human TREM1 (NP_061113.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ATKL TEEK YELK EGQT LDVK CDYT LEKF ASSQ KAWQ IIRD GEMP KTLA CTER PSKN SHPV QVGR IILE DYHD HGLL RVRM VNLQ VEDS GLYQ CVIY QPPK EPHM LFDR IR |
遺伝子ID: | 54210 |
Uniprot: | Q9NP99 |
セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
計算された分子量: | 17kDa/25kDa/26kDa |
観察された分子量: | 30kDa |
同義語: | TREM1, CD354, TREM-1 |
バックグラウンド: | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
UniProt Protein Function: | TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: integral to membrane; extracellular region; plasma membrane Molecular Function:receptor activity Biological Process: neutrophil chemotaxis; innate immune response; cytokine secretion during immune response; blood coagulation; leukocyte migration; chemokine metabolic process; humoral immune response |
NCBI Summary: | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
UniProt Code: | Q9NP99 |
NCBI GenInfo Identifier: | 50401685 |
NCBI Gene ID: | 54210 |
NCBI Accession: | Q9NP99.1 |
UniProt Secondary Accession: | Q9NP99,Q53FL8, Q5T2C9, Q86YU1, B4DWG2, K7EJW1, |
UniProt Related Accession: | Q9NP99 |
Molecular Weight: | 234 |
NCBI Full Name: | Triggering receptor expressed on myeloid cells 1 |
NCBI Synonym Full Names: | triggering receptor expressed on myeloid cells 1 |
NCBI Official Symbol: | TREM1 |
NCBI Official Synonym Symbols: | CD354; TREM-1 |
NCBI Protein Information: | triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1 |
UniProt Protein Name: | Triggering receptor expressed on myeloid cells 1 |
UniProt Synonym Protein Names: | Triggering receptor expressed on monocytes 1; CD_antigen: CD354 |
Protein Family: | Triggering receptor expressed on myeloid cells |
UniProt Gene Name: | TREM1 |
UniProt Entry Name: | TREM1_HUMAN |
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