Anti-TREH Antibody (CAB15397)
- SKU:
- CAB15397
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-TREH Antibody |
抗体コード: | CAB15397 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-556 of human TREH (NP_009111.2). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-556 of human TREH (NP_009111.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NAFL CQAE ELMS NFYS RLGN DSQA TKYR ILRS QRLA ALNT VLWD EQTG AWFD YDLE KKKK NREF YPSN LTPL WAGC FSDP GVAD KALK YLED NRIL TYQY GIPT SLQK TGQQ WDFP NAWA PLQD LVIR GLAK APLR RAQE VAFQ LAQN WIRT NFDV YSQK SAMY EKYD VSNG GQPG GGGE YEVQ EGFG WTNG VVLM LLDR YGDR LTS |
遺伝子ID: | 11181 |
Uniprot: | O43280 |
セルラーロケーション: | Cell membrane, GPI-anchor, Lipid-anchor |
計算された分子量: | 62kDa/66kDa |
観察された分子量: | Refer to figures |
同義語: | TREH, TRE, TREA, trehalase |
バックグラウンド: | This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | TREH: Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose. Deficiency of TREH results in isolated trehalose intolerance that causes gastrointestinal symptoms after ingestion of edible mushrooms. Belongs to the glycosyl hydrolase 37 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.2.1.28; Membrane protein, GPI anchor; Carbohydrate Metabolism - starch and sucrose; Hydrolase Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: anchored to plasma membrane; plasma membrane Molecular Function:alpha,alpha-trehalase activity Biological Process: polysaccharide digestion; organ morphogenesis; trehalose catabolic process; trehalose metabolic process; carbohydrate metabolic process; pathogenesis Disease: Trehalase Deficiency |
NCBI Summary: | This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
UniProt Code: | O43280 |
NCBI GenInfo Identifier: | 116284412 |
NCBI Gene ID: | 11181 |
NCBI Accession: | NP_009111.2 |
UniProt Secondary Accession: | O43280,Q32MB9, Q53FY8, |
UniProt Related Accession: | O43280 |
Molecular Weight: | 62,941 Da |
NCBI Full Name: | trehalase isoform 1 |
NCBI Synonym Full Names: | trehalase (brush-border membrane glycoprotein) |
NCBI Official Symbol: | TREH |
NCBI Official Synonym Symbols: | TRE; TREA |
NCBI Protein Information: | trehalase; alpha,alpha-trehalose glucohydrolase |
UniProt Protein Name: | Trehalase |
UniProt Synonym Protein Names: | Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase |
Protein Family: | Trehalase |
UniProt Gene Name: | TREH |
UniProt Entry Name: | TREA_HUMAN |
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