Anti-TMEM189 Antibody (CAB8380)
- SKU:
- CAB8380
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-TMEM189 Antibody |
抗体コード: | CAB8380 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human TMEM189 (NP_954580.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
反応性: | Human |
ポジティブサンプル: | MCF7 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human TMEM189 (NP_954580.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TLLQ DWHV ILPR KHHR IHHV SPHE TYFC ITTG WLNY PLEK IGFW RRLE DLIQ GLTG EKPR ADDM KWAQ KIK |
遺伝子ID: | 387521 |
Uniprot: | A5PLL7 |
セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
計算された分子量: | 30kDa/31kDa |
観察された分子量: | 31kDa |
同義語: | TMEM189, KUA |
バックグラウンド: | Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | TMEM189: 2 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral Chromosomal Location of Human Ortholog: 20q13.2 Cellular Component: cytoplasm; endoplasmic reticulum membrane; integral to membrane Molecular Function:ubiquitin protein ligase binding Biological Process: protein ubiquitination |
NCBI Summary: | Co-transcription of this gene and the neighboring downstream gene (ubiquitin-conjugating enzyme E2 variant 1) generates a rare read-through transcript, which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The protein encoded by this individual gene lacks a UEV1 domain but includes three transmembrane regions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009] |
UniProt Code: | A5PLL7 |
NCBI GenInfo Identifier: | 241982751 |
NCBI Gene ID: | 387521 |
NCBI Accession: | NP_001155977.1 |
UniProt Related Accession: | A5PLL7 |
Molecular Weight: | 30,851 Da |
NCBI Full Name: | transmembrane protein 189 isoform 2 |
NCBI Synonym Full Names: | transmembrane protein 189 |
NCBI Official Symbol: | TMEM189 |
NCBI Official Synonym Symbols: | KUA |
NCBI Protein Information: | transmembrane protein 189 |
UniProt Protein Name: | Transmembrane protein 189 |
Protein Family: | Transmembrane protein |
UniProt Gene Name: | TMEM189 |
UniProt Entry Name: | TM189_HUMAN |
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