Anti-Thyroglobulin Antibody (CAB3405)
- SKU:
- CAB3405
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AITD3
- Synonyms:
- TGN
Frequently bought together:
Description
抗体名: | Thyroglobulin Rabbit mAb |
抗体コード: | CAB3405 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | AITD3, TGN |
申し込み: | IHC, IF |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Thyroglobulin |
申し込み: | IHC, IF |
推奨される希釈: | IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human |
免疫原: | A synthesized peptide derived from human Thyroglobulin |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 7038 |
Uniprot: | P01266 |
計算された分子量: | 305kDa |
観察された分子量: | Refer to figures |
UniProt Protein Function: | Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). |
NCBI Summary: | Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009] |
UniProt Code: | P01266 |
NCBI GenInfo Identifier: | 126302607 |
NCBI Gene ID: | 7038 |
NCBI Accession: | P01266.5 |
UniProt Secondary Accession: | P01266,O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2 Q9UMZ0, Q9UNY3, |
UniProt Related Accession: | P01266 |
Molecular Weight: | 298,383 Da |
NCBI Full Name: | Thyroglobulin |
NCBI Synonym Full Names: | thyroglobulin |
NCBI Official Symbol: | TG |
NCBI Official Synonym Symbols: | TGN; AITD3 |
NCBI Protein Information: | thyroglobulin |
UniProt Protein Name: | Thyroglobulin |
Protein Family: | Thyroglobulin |
UniProt Gene Name: | TG |