Anti-THOC1 Antibody (CAB8179)
- SKU:
- CAB8179
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | THOC1 Rabbit Polyclonal Antibody |
抗体コード: | CAB8179 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 428-657 of human THOC1 (NP_005122.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BT-474, MCF7, A-549, HeLa, HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 428-657 of human THOC1 (NP_005122.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TKKI LMGN EELT RLWN LCPD NMEA CKSE TREH MPTL EEFF EEAI EQAD PENM VENE YKAV NNSN YGWR ALRL LARR SPHF FQPT NQQF KSLP EYLE NMVI KLAK ELPP PSEE IKTG EDED EEDN DALL KENE SPDV RRDK PVTG EQIE VFAN KLGE QWKI LAPY LEMK DSEI RQIE CDSE DMKM RAKQ LLVA WQDQ EGVH ATPE NLIN ALNK SGLS DLAE SLTN DNET NS |
遺伝子ID: | 9984 |
Uniprot: | Q96FV9 |
セルラーロケーション: | Cytoplasm, Cytoplasm, Nucleus, Nucleus matrix, Nucleus speckle, nucleoplasm |
計算された分子量: | 43kDa/75kDa |
観察された分子量: | 92kDa |
同義語: | THOC1, HPR1, P84, P84N5 |
バックグラウンド: |
UniProt Protein Function: | Tho1: a protein associated the nuclear matrix. Part of the TREX (transcription/export) complex. The TREX complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export. |
UniProt Protein Details: | Protein type:Spliceosome Chromosomal Location of Human Ortholog: 18p11.32 Cellular Component: cytoplasm; intercellular bridge; nuclear chromosome, telomeric region; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: apoptosis; intronless viral mRNA export from host nucleus; mRNA 3'-end processing; mRNA export from nucleus; negative regulation of isotype switching to IgA isotypes; positive regulation of RNA elongation; regulation of DNA recombination; regulation of RNA elongation; replication fork processing; RNA export from nucleus; RNA processing; termination of RNA polymerase II transcription |
NCBI Summary: | HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q96FV9 |
NCBI GenInfo Identifier: | 37999906 |
NCBI Gene ID: | 9984 |
NCBI Accession: | Q96FV9.1 |
UniProt Secondary Accession: | Q96FV9,Q15219, Q64I72, Q64I73, B2RBP6, |
UniProt Related Accession: | Q96FV9 |
Molecular Weight: | 43,359 Da |
NCBI Full Name: | THO complex subunit 1 |
NCBI Synonym Full Names: | THO complex 1 |
NCBI Official Symbol: | THOC1 |
NCBI Official Synonym Symbols: | P84; HPR1; P84N5 |
NCBI Protein Information: | THO complex subunit 1 |
UniProt Protein Name: | THO complex subunit 1 |
UniProt Synonym Protein Names: | Nuclear matrix protein p84; p84N5; hTREX84 |
UniProt Gene Name: | THOC1 |
UniProt Entry Name: | THOC1_HUMAN |
View AllClose