Anti-TFDP2 Antibody (CAB4152)
- SKU:
- CAB4152
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
抗体名: | Anti-TFDP2 Antibody |
抗体コード: | CAB4152 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 287-386 of human TFDP2 (NP_006277.1). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse heart, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 287-386 of human TFDP2 (NP_006277.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GYIT DIST GPSW LNQG LLLN STQS VSNL DLTT GATL PQSS VNQG LCLD AEVA LATG QFLA PNSH QSSS AASH CSES RGET PCSF NDED EEDD EEDS SSPE |
遺伝子ID: | 7029 |
Uniprot: | Q14188 |
セルラーロケーション: | Nucleus |
計算された分子量: | 34kDa/39kDa/40kDa/41kDa/42kDa/46kDa/49kDa |
観察された分子量: | 50kDa |
同義語: | TFDP2, DP2 |
バックグラウンド: | The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | TFDP2: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis. Belongs to the E2F/DP family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 3q23 Cellular Component: nucleoplasm; transcription factor complex Molecular Function:protein domain specific binding; DNA binding; transcription cofactor activity; transcription factor binding; transcription factor activity Biological Process: transcription initiation from RNA polymerase II promoter; Notch signaling pathway; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; gene expression; mitotic cell cycle |
NCBI Summary: | The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
UniProt Code: | Q14188 |
NCBI GenInfo Identifier: | 8039810 |
NCBI Gene ID: | 7029 |
NCBI Accession: | Q14188.2 |
UniProt Related Accession: | Q14188 |
Molecular Weight: | |
NCBI Full Name: | Transcription factor Dp-2 |
NCBI Synonym Full Names: | transcription factor Dp-2 |
NCBI Official Symbol: | TFDP2 |
NCBI Official Synonym Symbols: | DP2 |
NCBI Protein Information: | transcription factor Dp-2 |
UniProt Protein Name: | Transcription factor Dp-2 |
UniProt Synonym Protein Names: | E2F dimerization partner 2 |
UniProt Gene Name: | TFDP2 |
UniProt Entry Name: | TFDP2_HUMAN |
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