Anti-TCTN3 Antibody (CAB0684)
- SKU:
- CAB0684
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
抗体名: | Anti-TCTN3 Antibody |
抗体コード: | CAB0684 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-475 of human TCTN3 (NP_056446.4). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse craniofacial, Mouse lung, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-475 of human TCTN3 (NP_056446.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QTQS PPSF YRAG DPIL TYFP KWSV ISLL RQPA GVGA GGLC AESN PAGF LESK STTC TRFF KNLA SSCT LDSA LNAA SYYN FTVL KVPR SMTD PQNM EFQV PVIL TSQA NAPL LAGN TCQN VVSQ VTYE IETN GTFG IQKV SVSL GQTN LTVE PGAS LQQH FILR FRAF QQST AASL TSPR SGNP GYIV GKPL LALT DDIS YSMT LLQS QGNG SCSV KRHE VQFG VNAI SGCK LRLK KADC SHLQ QEIY QTLH GRPR PEYV AIFG NADP AQKG GWTR |
遺伝子ID: | 26123 |
Uniprot: | Q6NUS6 |
セルラーロケーション: | Membrane, Single-pass type I membrane protein |
計算された分子量: | 22kDa/47kDa/50kDa/66kDa |
観察された分子量: | 68kDa |
同義語: | TCTN3, C10orf61, JBTS18, OFD4, TECT3 |
バックグラウンド: | This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
UniProt Protein Function: | TCTN3: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation. Belongs to the tectonic family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Apoptosis; Membrane protein, integral Chromosomal Location of Human Ortholog: 10q24.1 Cellular Component: integral to membrane Biological Process: smoothened signaling pathway; apoptosis; organelle organization and biogenesis Disease: Joubert Syndrome 18; Joubert Syndrome 1; Orofaciodigital Syndrome Iv |
NCBI Summary: | This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012] |
UniProt Code: | Q6NUS6 |
NCBI GenInfo Identifier: | 91208025 |
NCBI Gene ID: | 26123 |
NCBI Accession: | Q6NUS6.2 |
UniProt Secondary Accession: | Q6NUS6,Q6P7P3, Q6UW27, Q6ZQQ0, Q8N7K1, Q8NBQ0, Q96GF7 Q9Y3U1, A6NIC8, B0QZ90, B4DR81, |
UniProt Related Accession: | Q6NUS6 |
Molecular Weight: | 607 |
NCBI Full Name: | Tectonic-3 |
NCBI Synonym Full Names: | tectonic family member 3 |
NCBI Official Symbol: | TCTN3 |
NCBI Official Synonym Symbols: | OFD4; TECT3; JBTS18; C10orf61 |
NCBI Protein Information: | tectonic-3 |
UniProt Protein Name: | Tectonic-3 |
Protein Family: | Tectonic |
UniProt Gene Name: | TCTN3 |
UniProt Entry Name: | TECT3_HUMAN |
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