Anti-TBX6 Antibody (CAB16979)
- SKU:
- CAB16979
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-TBX6 Antibody |
抗体コード: | CAB16979 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 191-300 of human TBX6 (NP_004599.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat thymus, Rat spleen, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 191-300 of human TBX6 (NP_004599.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SFHR VKLT NSTL DPHG HLIL HSMH KYQP RIHL VRAA QLCS QHWG GMAS FRFP ETTF ISVT AYQN PQIT QLKI AANP FAKG FREN GRNC KRER DARV KRKL RGPE PAAT EA |
遺伝子ID: | 6911 |
Uniprot: | O95947 |
セルラーロケーション: | |
計算された分子量: | 33kDa/47kDa |
観察された分子量: | 58kDa |
同義語: | TBX6, SCDO5, T-box 6 |
バックグラウンド: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. |
UniProt Protein Function: | TBX6: T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16p11.2 Molecular Function:protein binding Biological Process: anatomical structure morphogenesis; mesoderm development; negative regulation of transcription from RNA polymerase II promoter Disease: Deafness, Autosomal Recessive 67 |
NCBI Summary: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008] |
UniProt Code: | O95947 |
NCBI GenInfo Identifier: | 115502464 |
NCBI Gene ID: | 6911 |
NCBI Accession: | O95947.2 |
UniProt Secondary Accession: | O95947,Q8TAS4, Q9HA44, |
UniProt Related Accession: | O95947 |
Molecular Weight: | 33,197 Da |
NCBI Full Name: | T-box transcription factor TBX6 |
NCBI Synonym Full Names: | T-box 6 |
NCBI Official Symbol: | TBX6 |
NCBI Official Synonym Symbols: | SCDO5 |
NCBI Protein Information: | T-box transcription factor TBX6 |
UniProt Protein Name: | T-box transcription factor TBX6 |
Protein Family: | T-box transcription factor |
UniProt Gene Name: | TBX6 |
UniProt Entry Name: | TBX6_HUMAN |
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