Anti-TAL1 Antibody (CAB12927)
- SKU:
- CAB12927
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
抗体名: | Anti-TAL1 Antibody |
抗体コード: | CAB12927 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 242-331 of human TAL1 (NP_003180.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | Jurkat, HT-29, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 242-331 of human TAL1 (NP_003180.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LLND QEEE GTQR AKTG KDPV VGAG GGGG GGGG GAPP DDLL QDVL SPNS SCGS SLDG AASP DSYT EEPA PKHT ARSL HPAM LPAA DGAG PR |
遺伝子ID: | 6886 |
Uniprot: | P17542 |
セルラーロケーション: | Nucleus |
計算された分子量: | 16kDa/31kDa/34kDa |
観察された分子量: | 50kDa |
同義語: | TAL1, SCL, TCL5, bHLHa17, tal-1 |
バックグラウンド: |
UniProt Protein Function: | TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2. |
UniProt Protein Details: | Protein type:DNA-binding; Oncoprotein; Transcription factor Chromosomal Location of Human Ortholog: 1p32 Cellular Component: histone deacetylase complex; nuclear chromatin; nucleus; transcription factor complex Molecular Function:chromatin binding; enzyme binding; histone deacetylase binding; protein binding; transcription factor activity Biological Process: basophil differentiation; cell fate commitment; embryonic hemopoiesis; erythrocyte differentiation; hemopoiesis; megakaryocyte differentiation; positive regulation of cell division; positive regulation of chromatin assembly or disassembly; positive regulation of erythrocyte differentiation; positive regulation of mitotic cell cycle; positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter Disease: Leukemia, Acute Lymphoblastic |
UniProt Code: | P17542 |
NCBI GenInfo Identifier: | 134305 |
NCBI Gene ID: | 6886 |
NCBI Accession: | P17542.2 |
UniProt Secondary Accession: | P17542,D3DQ24, |
UniProt Related Accession: | P17542 |
Molecular Weight: | 16,548 Da |
NCBI Full Name: | T-cell acute lymphocytic leukemia protein 1 |
NCBI Synonym Full Names: | TAL bHLH transcription factor 1, erythroid differentiation factor |
NCBI Official Symbol: | TAL1 |
NCBI Official Synonym Symbols: | SCL; TCL5; tal-1; bHLHa17 |
NCBI Protein Information: | T-cell acute lymphocytic leukemia protein 1 |
UniProt Protein Name: | T-cell acute lymphocytic leukemia protein 1 |
UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5 |
Protein Family: | Transaldolase |
UniProt Gene Name: | TAL1 |
UniProt Entry Name: | TAL1_HUMAN |