Anti-SV2B Antibody (CAB16269)
- SKU:
- CAB16269
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
抗体名: | Anti-SV2B Antibody |
抗体コード: | CAB16269 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 415-540 of human SV2B (NP_055663.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 415-540 of human SV2B (NP_055663.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | IRYF QDEE YKSK MKVF FGEH VYGA TINF TMEN QIHQ HGKL VNDK FTRM YFKH VLFE DTFF DECY FEDV TSTD TYFK NCTI ESTI FYNT DLYE HKFI NCRF INST FLEQ KEGC HMDL EQDN DFLI YL |
遺伝子ID: | 9899 |
Uniprot: | Q7L1I2 |
セルラーロケーション: | |
計算された分子量: | 60kDa/77kDa |
観察された分子量: | Refer to figures |
同義語: | SV2B, HsT19680 |
バックグラウンド: | This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. |
UniProt Protein Function: | SV2B: Probably plays a role in the control of regulated secretion in neural and endocrine cells. Belongs to the major facilitator superfamily. |
UniProt Protein Details: | Protein type:Vesicle; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 15q26.1 Cellular Component: synaptic vesicle; membrane; synaptic vesicle membrane; integral to membrane; plasma membrane; acrosome; cell junction Molecular Function:transmembrane transporter activity Biological Process: neurotransmitter transport; pathogenesis; transmembrane transport |
UniProt Code: | Q7L1I2 |
NCBI GenInfo Identifier: | 262399383 |
NCBI Gene ID: | 9899 |
NCBI Accession: | NP_001161052.1 |
UniProt Secondary Accession: | Q7L1I2,O94840, Q6IAR8, B4DH30, C6G489, |
UniProt Related Accession: | Q7L1I2 |
Molecular Weight: | 77,444 Da |
NCBI Full Name: | synaptic vesicle glycoprotein 2B isoform 2 |
NCBI Synonym Full Names: | synaptic vesicle glycoprotein 2B |
NCBI Official Symbol: | SV2B |
NCBI Official Synonym Symbols: | HsT19680 |
NCBI Protein Information: | synaptic vesicle glycoprotein 2B; synaptic vesicle protein 2B homolog |
UniProt Protein Name: | Synaptic vesicle glycoprotein 2B |
Protein Family: | Synaptic vesicle glycoprotein |
UniProt Gene Name: | SV2B |
UniProt Entry Name: | SV2B_HUMAN |
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