Anti-SPTLC2 Antibody (CAB11716)
- SKU:
- CAB11716
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SPTLC2 Antibody |
抗体コード: | CAB11716 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 423-562 of human SPTLC2 (NP_004854.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BxPC-3, U-87MG, 293T, Mouse kidney, Mouse stomach |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 423-562 of human SPTLC2 (NP_004854.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MKCI MGQD GTSL GKEC VQQL AENT RYFR RRLK EMGF IIYG NEDS PVVP LMLY MPAK IGAF GREM LKRN IGVV VVGF PATP IIES RARF CLSA AHTK EILD TALK EIDE VGDL LQLK YSRH RLVP LLDR PFDE TTYE ETED |
遺伝子ID: | 9517 |
Uniprot: | O15270 |
セルラーロケーション: | Endoplasmic reticulum membrane, Single-pass membrane protein |
計算された分子量: | 62kDa |
観察された分子量: | 58kDa |
同義語: | SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a |
バックグラウンド: | This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. |
NCBI Summary: | This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011] |
UniProt Code: | O15270 |
NCBI GenInfo Identifier: | 6685580 |
NCBI Gene ID: | 9517 |
NCBI Accession: | O15270.1 |
UniProt Related Accession: | O15270 |
Molecular Weight: | ~ 58kDa |
NCBI Full Name: | Serine palmitoyltransferase 2 |
NCBI Synonym Full Names: | serine palmitoyltransferase long chain base subunit 2 |
NCBI Official Symbol: | SPTLC2 |
NCBI Official Synonym Symbols: | LCB2; SPT2; HSN1C; LCB2A; NSAN1C; hLCB2a |
NCBI Protein Information: | serine palmitoyltransferase 2 |
UniProt Protein Name: | Serine palmitoyltransferase 2 |
UniProt Synonym Protein Names: | Long chain base biosynthesis protein 2; LCB 2; Long chain base biosynthesis protein 2a; LCB2a; Serine-palmitoyl-CoA transferase 2; SPT 2 |
Protein Family: | Serine palmitoyltransferase |
UniProt Gene Name: | SPTLC2 |
UniProt Entry Name: | SPTC2_HUMAN |
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