Anti-SOAT1 Antibody (CAB6311)
- SKU:
- CAB6311
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SOAT1 Antibody |
抗体コード: | CAB6311 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SOAT1 (NP_003092.4). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | H460, HeLa, SW480, Mouse stomach, Mouse liver, Rat liver, Rat stomach |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SOAT1 (NP_003092.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVGE EKMS LRNR LSKS RENP EEDE DQRN PAKE SLET PSNG RIDI KQLI AKKI KLTA EAEE LKPF FMKE VGSH FDDF VTNL IEKS ASLD NGGC ALTT FSVL EGEK NNHR AKDL RAPP EQGK IFIA RRSL LD |
遺伝子ID: | 6646 |
Uniprot: | P35610 |
セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
計算された分子量: | 57kDa/58kDa/64kDa |
観察された分子量: | 55kDa |
同義語: | SOAT1, ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT |
バックグラウンド: | The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. |
UniProt Protein Function: | SOAT1: Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. |
UniProt Protein Details: | Protein type:Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; EC 2.3.1.26; Transferase; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1q25 Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane Molecular Function:protein binding; acyl-CoA binding; sterol O-acyltransferase activity; cholesterol binding Biological Process: cholesterol metabolic process; cholesterol homeostasis; cholesterol efflux; positive regulation of amyloid precursor protein biosynthetic process |
NCBI Summary: | The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | P35610 |
NCBI GenInfo Identifier: | 33302623 |
NCBI Gene ID: | 6646 |
NCBI Accession: | P35610.3 |
UniProt Secondary Accession: | P35610,Q5T0X4, Q8N1E4, A6NC40, A8K3P4, A9Z1V7, B4DU95 |
UniProt Related Accession: | P35610 |
Molecular Weight: | 550 |
NCBI Full Name: | Sterol O-acyltransferase 1 |
NCBI Synonym Full Names: | sterol O-acyltransferase 1 |
NCBI Official Symbol: | SOAT1 |
NCBI Official Synonym Symbols: | ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1 |
NCBI Protein Information: | sterol O-acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase 1; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 |
UniProt Protein Name: | Sterol O-acyltransferase 1 |
UniProt Synonym Protein Names: | Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1; Cholesterol acyltransferase 1 |
Protein Family: | Sterol O-acyltransferase |
UniProt Gene Name: | SOAT1 |
UniProt Entry Name: | SOAT1_HUMAN |
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