Anti-SMARCD2 Antibody (CAB12104)
- SKU:
- CAB12104
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SMARCD2 Antibody |
抗体コード: | CAB12104 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 454-531 of human SMARCD2 (NP_001091896.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | HT-29, HeLa, LO2, Jurkat, BxPC-3, Mouse thymus, Mouse spleen |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 454-531 of human SMARCD2 (NP_001091896.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RDFM LSFS TDPQ DFIQ EWLR SQRR DLKI ITDV IGNP EEER RAAF YHQP WAQE AVGR HIFA KVQQ RRQE LEQV LGIR LT |
遺伝子ID: | 6603 |
Uniprot: | Q92925 |
セルラーロケーション: | Nucleus |
計算された分子量: | 55kDa/57kDa/58kDa |
観察された分子量: | 64kDa |
同義語: | SMARCD2, BAF60B, CRACD2, PRO2451, Rsc6p, SGD2 |
バックグラウンド: | The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | SMARCD2: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the SMARCD family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: nuclear chromatin; nucleoplasm; protein complex; SWI/SNF complex Molecular Function:nucleosomal DNA binding; protein binding Biological Process: ATP-dependent chromatin remodeling; chromatin remodeling; nucleosome disassembly |
NCBI Summary: | The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q92925 |
NCBI GenInfo Identifier: | 322510105 |
NCBI Gene ID: | 6603 |
NCBI Accession: | Q92925.3 |
UniProt Secondary Accession: | Q92925,Q7L2I6, Q9UHZ1, A5PLL5, A6NNQ7, B4DV56, B4E1R6 |
UniProt Related Accession: | Q92925 |
Molecular Weight: | 59kDa |
NCBI Full Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 |
NCBI Synonym Full Names: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
NCBI Official Symbol: | SMARCD2 |
NCBI Official Synonym Symbols: | Rsc6p; BAF60B; CRACD2; PRO2451 |
NCBI Protein Information: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 |
UniProt Protein Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 |
UniProt Synonym Protein Names: | 60 kDa BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; BAF60B |
Protein Family: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily |
UniProt Gene Name: | SMARCD2 |
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