Anti-SLIT1 Antibody (CAB16430)
- SKU:
- CAB16430
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-SLIT1 Antibody |
抗体コード: | CAB16430 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1315-1534 of human SLIT1 (NP_003052.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RNLY INNE LQDF TKTQ MKPG VVPG CEPC RKLY CLHG ICQP NATP GPMC HCEA GWVG LHCD QPAD GPCH GHKC VHGQ CVPL DALS YSCQ CQDG YSGA LCNQ AGAL AEPC RGLQ CLHG HCQA SGTK GAHC VCDP GFSG ELCE QESE CRGD PVRD FHQV QRGY AICQ TTRP LSWV ECRG SCPG QGCC QGLR LKRR KFTF ECSD GTSF AEEV EKPT KCGC ALCA |
遺伝子ID: | 6585 |
Uniprot: | O75093 |
セルラーロケーション: | Secreted |
計算された分子量: | 90kDa/167kDa |
観察された分子量: | 168kDa |
同義語: | SLIT1, MEGF4, SLIL1, SLIT-1, SLIT3 |
バックグラウンド: |
UniProt Protein Function: | SLIT1: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 10q23.3-q24 Cellular Component: extracellular space; proteinaceous extracellular matrix Molecular Function:heparin binding; Roundabout binding Biological Process: axon extension involved in axon guidance; axon guidance; chemorepulsion involved in embryonic olfactory bulb interneuron migration; motor axon guidance; negative chemotaxis; negative regulation of synaptogenesis; regulation of axonogenesis |
UniProt Code: | O75093 |
NCBI GenInfo Identifier: | 145559530 |
NCBI Gene ID: | 6585 |
NCBI Accession: | O75093.4 |
UniProt Secondary Accession: | O75093,Q5T0V1, Q8WWZ2, Q9UIL7, |
UniProt Related Accession: | O75093 |
Molecular Weight: | 90,633 Da |
NCBI Full Name: | Slit homolog 1 protein |
NCBI Synonym Full Names: | slit guidance ligand 1 |
NCBI Official Symbol: | SLIT1 |
NCBI Official Synonym Symbols: | MEGF4; SLIL1; SLIT3; SLIT-1 |
NCBI Protein Information: | slit homolog 1 protein |
UniProt Protein Name: | Slit homolog 1 protein |
UniProt Synonym Protein Names: | Multiple epidermal growth factor-like domains protein 4; Multiple EGF-like domains protein 4 |
Protein Family: | Slit homolog 1 protein |
UniProt Gene Name: | SLIT1 |
UniProt Entry Name: | SLIT1_HUMAN |
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