Anti-SLC9A8 Antibody (CAB12829)
- SKU:
- CAB12829
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC9A8 Antibody |
抗体コード: | CAB12829 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 472-581 of human SLC9A8 (NP_056081.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 472-581 of human SLC9A8 (NP_056081.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RLMD IEDA KAHR RNKK DVNL SKTE KMGN TVES EHLS ELTE EEYE AHYI RRQD LKGF VWLD AKYL NPFF TRRL TQED LHHG RIQM KTLT NKWY EEVR QGPS GSED DEQE LL |
遺伝子ID: | 23315 |
Uniprot: | Q9Y2E8 |
セルラーロケーション: | Golgi apparatus membrane, Multi-pass membrane protein |
計算された分子量: | 65kDa/67kDa |
観察された分子量: | 65kDa |
同義語: | SLC9A8, NHE-8, NHE8 |
バックグラウンド: |
UniProt Protein Function: | NHE8: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 20q13.13 Cellular Component: Golgi membrane; integral to membrane Molecular Function:potassium:hydrogen antiporter activity; sodium:hydrogen antiporter activity Biological Process: ion transport; regulation of intracellular pH; transmembrane transport |
NCBI Summary: | Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009] |
UniProt Code: | Q9Y2E8 |
NCBI GenInfo Identifier: | 254763448 |
NCBI Gene ID: | 23315 |
NCBI Accession: | Q9Y2E8.4 |
UniProt Secondary Accession: | Q9Y2E8,Q2M1U9, Q68CZ8, Q9BX15, Q9Y507, B4DTQ8, |
UniProt Related Accession: | Q9Y2E8 |
Molecular Weight: | 67,275 Da |
NCBI Full Name: | Sodium/hydrogen exchanger 8 |
NCBI Synonym Full Names: | solute carrier family 9 member A8 |
NCBI Official Symbol: | SLC9A8 |
NCBI Official Synonym Symbols: | NHE8; NHE-8 |
NCBI Protein Information: | sodium/hydrogen exchanger 8 |
UniProt Protein Name: | Sodium/hydrogen exchanger 8 |
UniProt Synonym Protein Names: | Na(+)/H(+) exchanger 8; NHE-8; Solute carrier family 9 member 8 |
UniProt Gene Name: | SLC9A8 |
UniProt Entry Name: | SL9A8_HUMAN |
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