Anti-SLC9A3R1 Antibody (CAB0146)
- SKU:
- CAB0146
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SLC9A3R1 Antibody |
抗体コード: | CAB0146 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 189-358 of human SLC9A3R1 (NP_004243.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:4000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, 293T, HT-29, MCF7, Mouse liver, Mouse kidney, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 189-358 of human SLC9A3R1 (NP_004243.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EASG LRAQ DRIV EVNG VCME GKQH GDVV SAIR AGGD ETKL LVVD RETD EFFK KCRV IPSQ EHLN GPLP VPFT NGEI QKEN SREA LAEA ALES PRPA LVRS ASSD TSEE LNSQ DSPP KQDS TAPS STSS SDPI LDFN ISLA MAKE RAHQ KRSS KRAP QMDW SKKN ELFS NL |
遺伝子ID: | 9368 |
Uniprot: | O14745 |
セルラーロケーション: | Apical cell membrane, Cell projection, Cytoplasm, Endomembrane system, Peripheral membrane protein, filopodium, microvillus, ruffle |
計算された分子量: | 22kDa/38kDa |
観察された分子量: | 50kDa |
同義語: | SLC9A3R1, EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2 |
バックグラウンド: | This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. |
NCBI Summary: | This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009] |
UniProt Code: | O14745 |
NCBI GenInfo Identifier: | 4759140 |
NCBI Gene ID: | 9368 |
NCBI Accession: | NP_004243.1 |
UniProt Secondary Accession: | O14745,Q9JJ19, |
UniProt Related Accession: | O14745 |
Molecular Weight: | 50kDa |
NCBI Full Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 |
NCBI Synonym Full Names: | SLC9A3 regulator 1 |
NCBI Official Symbol: | SLC9A3R1 |
NCBI Official Synonym Symbols: | EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2 |
NCBI Protein Information: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 |
UniProt Protein Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 |
UniProt Synonym Protein Names: | Ezrin-radixin-moesin-binding phosphoprotein 50; EBP50; Regulatory cofactor of Na(+)/H(+) exchanger; Sodium-hydrogen exchanger regulatory factor 1; Solute carrier family 9 isoform A3 regulatory factor 1 |
UniProt Gene Name: | SLC9A3R1 |
UniProt Entry Name: | NHRF1_HUMAN |
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