Anti-SLC7A7 Antibody (CAB17586)
- SKU:
- CAB17586
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-SLC7A7 Antibody |
抗体コード: | CAB17586 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-511 of human SLC7A7 (NP_001119577.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-511 of human SLC7A7 (NP_001119577.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SGLP FYFL IIRV PEHK RPLY LRRI VGSA TRYL QVLC MSVA AEMD LEDG GEMP KQRD PKSN |
遺伝子ID: | 9056 |
Uniprot: | Q9UM01 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1, SLC7A7 |
バックグラウンド: | The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011] |
UniProt Protein Function: | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. |
NCBI Summary: | The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011] |
UniProt Code: | Q9UM01 |
NCBI GenInfo Identifier: | 186910306 |
NCBI Gene ID: | 9056 |
NCBI Accession: | NP_001119577.1 |
UniProt Related Accession: | Q9UM01 |
Molecular Weight: | |
NCBI Full Name: | Y+L amino acid transporter 1 |
NCBI Synonym Full Names: | solute carrier family 7 member 7 |
NCBI Official Symbol: | SLC7A7 |
NCBI Official Synonym Symbols: | LPI; LAT3; MOP-2; Y+LAT1; y+LAT-1 |
NCBI Protein Information: | Y+L amino acid transporter 1 |
UniProt Protein Name: | Y+L amino acid transporter 1 |
UniProt Synonym Protein Names: | Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 |
Protein Family: | Y+L amino acid transporter |
UniProt Gene Name: | SLC7A7 |