Anti-SLC7A2 Antibody (CAB14574)
- SKU:
- CAB14574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC7A2 Antibody |
抗体コード: | CAB14574 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC7A2 (NP_001008539.3). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, HepG2, HeLa, Mouse liver, Mouse brain, Rat liver |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC7A2 (NP_001008539.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | FLAF LVLG LSVL TTYG VHAI TRLE AWSL ALLA LFLV LFVA IVLT IWRQ PQNQ QKVA FMVP FLPF LPAF SILV NIYL MVQL SADT WVRF SIWM AIGF LIYF SYGI RHSL EGHL RDEN NEED AYPD NVHA AAEE KSAI QAND HHPR NLSS PFIF HEKT SEF |
遺伝子ID: | 6542 |
Uniprot: | P52569 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 71kDa/75kDa/76kDa |
観察された分子量: | 72kDa |
同義語: | SLC7A2, ATRC2, CAT2, HCAT2 |
バックグラウンド: | The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport. |
NCBI Summary: | The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P52569 |
NCBI GenInfo Identifier: | 258614005 |
NCBI Gene ID: | 6542 |
NCBI Accession: | NP_001008539.3 |
UniProt Secondary Accession: | P52569,O15291, O15292, Q14CQ6, Q6NSZ7, Q86TC6, B7ZL54 |
UniProt Related Accession: | P52569 |
Molecular Weight: | 75,986 Da |
NCBI Full Name: | cationic amino acid transporter 2 isoform 2 |
NCBI Synonym Full Names: | solute carrier family 7 member 2 |
NCBI Official Symbol: | SLC7A2 |
NCBI Official Synonym Symbols: | CAT2; ATRC2; HCAT2 |
NCBI Protein Information: | cationic amino acid transporter 2 |
UniProt Protein Name: | Cationic amino acid transporter 2 |
UniProt Synonym Protein Names: | Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 |
Protein Family: | Catalase isozyme |
UniProt Gene Name: | SLC7A2 |
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