Anti-SLC7A11 Antibody (CAB13685)
- SKU:
- CAB13685
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC7A11 Antibody |
抗体コード: | CAB13685 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A11 (NP_055146.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse liver, Mouse kidney, Rat liver |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A11 (NP_055146.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ILEP FFIQ CEIP ELAI KLIT AVGI TVVM VLNS MSVS WSAR IQIF LTFC KLTA ILII IVPG VMQL IKGQ TQNF KDAF SGRD SSIT RLPL AFYY GMYA YAGW F |
遺伝子ID: | 23657 |
Uniprot: | Q9UPY5 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 55kDa |
観察された分子量: | 37kDa/55kDa |
同義語: | SLC7A11, CCBR1, xCT |
バックグラウンド: | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
UniProt Protein Function: | Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. |
NCBI Summary: | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011] |
UniProt Code: | Q9UPY5 |
NCBI GenInfo Identifier: | 7657683 |
NCBI Gene ID: | 23657 |
NCBI Accession: | NP_055146.1 |
UniProt Secondary Accession: | Q9UPY5,A8K2U4, |
UniProt Related Accession: | Q9UPY5 |
Molecular Weight: | Observed: 40 kDa-45 kDaPredicted: 56 kDa |
NCBI Full Name: | cystine/glutamate transporter |
NCBI Synonym Full Names: | solute carrier family 7 member 11 |
NCBI Official Symbol: | SLC7A11 |
NCBI Official Synonym Symbols: | xCT; CCBR1 |
NCBI Protein Information: | cystine/glutamate transporter |
UniProt Protein Name: | Cystine/glutamate transporter |
UniProt Synonym Protein Names: | Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT |
Protein Family: | Protein XAP5 CIRCADIAN TIMEKEEPER |
UniProt Gene Name: | SLC7A11 |
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