Anti-SLC5A1 Antibody (CAB11976)
- SKU:
- CAB11976
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC5A1 Antibody |
抗体コード: | CAB11976 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC5A1 (NP_000334.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | 293T, HeLa, Mouse uterus |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human SLC5A1 (NP_000334.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ECEK YCGT KVGC TNIA YPTL VVEL MPNG LRGL MLSV MLAS LMSS LTSI FNSA STLF TMDI YAKV RKRA SEKE LMIA GRLF ILVL IGIS IAWV PIVQ SAQS G |
遺伝子ID: | 6523 |
Uniprot: | P13866 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 60kDa/73kDa |
観察された分子量: | 73kDa |
同義語: | SLC5A1, D22S675, NAGT, SGLT1 |
バックグラウンド: | This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | SLC5A1: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. Expressed mainly in intestine and kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter Chromosomal Location of Human Ortholog: 22q12.3 Cellular Component: brush border membrane; integral to plasma membrane; apical plasma membrane; plasma membrane; intercellular junction Molecular Function:protein binding; glucose:sodium symporter activity Biological Process: hexose transport; carbohydrate metabolic process; sodium ion transport; pathogenesis; glucose transport; metanephros development; transmembrane transport; intestinal absorption Disease: Glucose/galactose Malabsorption |
NCBI Summary: | This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | P13866 |
NCBI GenInfo Identifier: | 127803 |
NCBI Gene ID: | 6523 |
NCBI Accession: | P13866.1 |
UniProt Secondary Accession: | P13866,B2R7E2, B7Z4Q9, B7ZA69, |
UniProt Related Accession: | P13866 |
Molecular Weight: | 664 |
NCBI Full Name: | Sodium/glucose cotransporter 1 |
NCBI Synonym Full Names: | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
NCBI Official Symbol: | SLC5A1 |
NCBI Official Synonym Symbols: | NAGT; SGLT1; D22S675 |
NCBI Protein Information: | sodium/glucose cotransporter 1; Na+/glucose cotransporter 1; high affinity sodium-glucose cotransporter |
UniProt Protein Name: | Sodium/glucose cotransporter 1 |
UniProt Synonym Protein Names: | High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1 |
Protein Family: | Sodium/glucose cotransporter |
UniProt Gene Name: | SLC5A1 |
UniProt Entry Name: | SC5A1_HUMAN |
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