Anti-SLC30A7 Antibody (CAB5172)
- SKU:
- CAB5172
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLC30A7 Antibody |
| 抗体コード: | CAB5172 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 287-376 of human SLC30A7 (NP_598003.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 287-376 of human SLC30A7 (NP_598003.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RESV GILM QRTP PLLE NSLP QCYQ RVQQ LQGV YSLQ EQHF WTLC SDVY VGTL KLIV APDA DARW ILSQ THNI FTQA GVRQ LYVQ IDFA AM |
| 遺伝子ID: | 148867 |
| Uniprot: | Q8NEW0 |
| セルラーロケーション: | Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane |
| 計算された分子量: | 41kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | SLC30A7, ZNT7, ZnT-7, ZnTL2 |
| バックグラウンド: |
| UniProt Protein Function: | SLC30A7: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. |
| UniProt Protein Details: | Protein type:Transporter; Transporter, SLC family; Membrane protein, integral; Vesicle; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p21.2 Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; cytoplasmic membrane-bound vesicle; cytoplasm; integral to membrane; vesicle Molecular Function:cation transmembrane transporter activity Biological Process: sequestering of zinc ion; cellular protein metabolic process; zinc ion transport; transmembrane transport |
| NCBI Summary: | Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NEW0 |
| NCBI GenInfo Identifier: | 74751261 |
| NCBI Gene ID: | 148867 |
| NCBI Accession: | Q8NEW0.1 |
| UniProt Secondary Accession: | Q8NEW0,Q8TCH2, B2R949, D3DT61, |
| UniProt Related Accession: | Q8NEW0 |
| Molecular Weight: | 41kDa |
| NCBI Full Name: | Zinc transporter 7 |
| NCBI Synonym Full Names: | solute carrier family 30 (zinc transporter), member 7 |
| NCBI Official Symbol: | SLC30A7 |
| NCBI Official Synonym Symbols: | ZNT7; ZnT-7; ZnTL2 |
| NCBI Protein Information: | zinc transporter 7; zinc transporter ZnT-7; znt-like transporter 2; zinc transporter like 2; solute carrier family 30 member 7 |
| UniProt Protein Name: | Zinc transporter 7 |
| UniProt Synonym Protein Names: | Solute carrier family 30 member 7; Znt-like transporter 2 |
| Protein Family: | Zinc transporter |
| UniProt Gene Name: | SLC30A7 |
| UniProt Entry Name: | ZNT7_HUMAN |
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