Anti-SLC27A1 Antibody (CAB12847)
- SKU:
- CAB12847
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SLC27A1 Antibody |
抗体コード: | CAB12847 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U2OS, MCF-7, Mouse skeletal muscle, Mouse heart, Rat heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 347-646 of human SLC27A1 (NP_940982.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QPVR EAER RHRV RLAV GNGL RPAI WEEF TERF GVRQ IGEF YGAT ECNC SIAN MDGK VGSC GFNS RILP HVYP IRLV KVNE DTME LLRD AQGL CIPC QAGE PGLL VGQI NQQD PLRR FDGY VSES ATSK KIAH SVFS KGDS AYLS GDVL VMDE LGYM YFRD RSGD TFRW RGEN VSTT EVEG VLSR LLGQ TDVA VYGV AVPG VEGK AGMA AVAD PHSL LDPN AIYQ ELQK VLAP YARP IFLR LLPQ VDTT GTFK IQKT RLQR EGFD PRQT SDRL FFLD LKQG HYLP LNEA VYTR ICSG AFAL |
遺伝子ID: | 376497 |
Uniprot: | Q6PCB7 |
セルラーロケーション: | Cell membrane, Cytoplasm, Endomembrane system, Single-pass membrane protein |
計算された分子量: | 51kDa/71kDa |
観察された分子量: | 71kDa |
同義語: | SLC27A1, ACSVL5, FATP, FATP-1, FATP1 |
バックグラウンド: |
UniProt Protein Function: | SLC27A1: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family. |
UniProt Protein Details: | Protein type:EC 6.2.1.-; Ligase; Lipid-binding; Membrane protein, integral; Mitochondrial; Vesicle Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: membrane; plasma membrane Molecular Function:fatty acid transporter activity Biological Process: cardiolipin biosynthetic process; long-chain fatty acid transport; phosphatidic acid biosynthetic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylglycerol biosynthetic process; phosphatidylinositol biosynthetic process; phosphatidylserine biosynthetic process |
UniProt Code: | Q6PCB7 |
NCBI GenInfo Identifier: | 38524616 |
NCBI Gene ID: | 376497 |
NCBI Accession: | NP_940982.1 |
UniProt Secondary Accession: | Q6PCB7,A6NIH2, B7Z662, |
UniProt Related Accession: | Q6PCB7 |
Molecular Weight: | |
NCBI Full Name: | long-chain fatty acid transport protein 1 |
NCBI Synonym Full Names: | solute carrier family 27 member 1 |
NCBI Official Symbol: | SLC27A1 |
NCBI Official Synonym Symbols: | FATP; FATP1; ACSVL5; FATP-1 |
NCBI Protein Information: | long-chain fatty acid transport protein 1 |
UniProt Protein Name: | Long-chain fatty acid transport protein 1 |
UniProt Synonym Protein Names: | Solute carrier family 27 member 1 |
UniProt Gene Name: | SLC27A1 |
UniProt Entry Name: | S27A1_HUMAN |
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