Anti-SLC22A7 Antibody (CAB15137)
- SKU:
- CAB15137
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC22A7 Antibody |
抗体コード: | CAB15137 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-142 of human SLC22A7 (NP_696961.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, HT-29, mouse liver, mouse kidney, rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-142 of human SLC22A7 (NP_696961.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ALPG APAN FSHQ DVWL EAHL PREP DGTL SSCL RFAY PQAL PNTT LGEE RQSR GELE DEPA TVPC SQGW EYDH SEFS STIA TESQ WDLV CEQK G |
遺伝子ID: | 10864 |
Uniprot: | Q9Y694 |
セルラーロケーション: | Basolateral cell membrane, Multi-pass membrane protein |
計算された分子量: | 26kDa/59kDa/60kDa |
観察された分子量: | 60kDa |
同義語: | SLC22A7, NLT, OAT2, hOAT11 |
バックグラウンド: | The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. |
UniProt Protein Function: | SLC22A7: Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha- ketoglutarate. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; plasma membrane Molecular Function:sodium-independent organic anion transmembrane transporter activity Biological Process: transmembrane transport; organic anion transport |
NCBI Summary: | The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y694 |
NCBI GenInfo Identifier: | 74753520 |
NCBI Gene ID: | 10864 |
NCBI Accession: | Q9Y694.1 |
UniProt Related Accession: | Q9Y694 |
Molecular Weight: | 60kDa |
NCBI Full Name: | Solute carrier family 22 member 7 |
NCBI Synonym Full Names: | solute carrier family 22 member 7 |
NCBI Official Symbol: | SLC22A7 |
NCBI Official Synonym Symbols: | NLT; OAT2; hOAT11 |
NCBI Protein Information: | solute carrier family 22 member 7 |
UniProt Protein Name: | Solute carrier family 22 member 7 |
UniProt Synonym Protein Names: | Novel liver transporter; Organic anion transporter 2; hOAT2 |
Protein Family: | Solute carrier family |
UniProt Gene Name: | SLC22A7 |
UniProt Entry Name: | S22A7_HUMAN |
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