Anti-SLC20A1 Antibody (CAB4117)
- SKU:
- CAB4117
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-SLC20A1 Antibody |
抗体コード: | CAB4117 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 257-356 of human SLC20A1 (NP_005406.3). |
申し込み: | WB IF |
推奨希釈: | WB 1:200 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 293T, A-431, HeLa, HT-1080, NCI-H460, Mouse liver, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 257-356 of human SLC20A1 (NP_005406.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KIER EIKC SPSE SPLM EKKN SLKE DHEE TKLS VGDI ENKH PVSE VGPA TVPL QAVV EERT VSFK LGDL EEAP ERER LPSV DLKE ETSI DSTV NGAV QLPN |
遺伝子ID: | 6574 |
Uniprot: | Q8WUM9 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 73kDa |
観察された分子量: | 70-100kDa |
同義語: | SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1 |
バックグラウンド: | The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus. |
UniProt Protein Function: | SLC20A1: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter Chromosomal Location of Human Ortholog: 2q13 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:signal transducer activity; high affinity inorganic phosphate:sodium symporter activity; receptor activity; sodium:phosphate symporter activity; inorganic phosphate transmembrane transporter activity Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; transport; ion transport; signal transduction; transmembrane transport; phosphate metabolic process |
NCBI Summary: | The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011] |
UniProt Code: | Q8WUM9 |
NCBI GenInfo Identifier: | 74730735 |
NCBI Gene ID: | 6574 |
NCBI Accession: | Q8WUM9.1 |
UniProt Secondary Accession: | Q8WUM9,Q08344, Q6DHX8, Q9UQ82, |
UniProt Related Accession: | Q8WUM9 |
Molecular Weight: | 679 |
NCBI Full Name: | Sodium-dependent phosphate transporter 1 |
NCBI Synonym Full Names: | solute carrier family 20 (phosphate transporter), member 1 |
NCBI Official Symbol: | SLC20A1 |
NCBI Official Synonym Symbols: | PIT1; GLVR1; PiT-1; Glvr-1 |
NCBI Protein Information: | sodium-dependent phosphate transporter 1; leukemia virus receptor 1 homolog; solute carrier family 20 member 1; gibbon ape leukemia virus receptor 1 |
UniProt Protein Name: | Sodium-dependent phosphate transporter 1 |
UniProt Synonym Protein Names: | Gibbon ape leukemia virus receptor 1; GLVR-1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; PiT-1; Solute carrier family 20 member 1 |
UniProt Gene Name: | SLC20A1 |
UniProt Entry Name: | S20A1_HUMAN |
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