Anti-SLC19A1 Antibody (CAB14644)
- SKU:
- CAB14644
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC19A1 Antibody |
抗体コード: | CAB14644 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_919231.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_919231.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LDGL RHCQ RGHH PRQP PAQG LRSA AEEK AAQA LSVQ DKGL GGLQ PAQS PPLS PEDS LGAV GPAS LEQR QSDP YLAQ APAP QAAE FLSP VTTP SPCT LCSA QASG PEAA DETC PQLA VHPP GVSK LGLQ CLPS DGVQ NVNQ |
遺伝子ID: | 6573 |
Uniprot: | P41440 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 54kDa/60kDa/64kDa |
観察された分子量: | Refer to figures |
同義語: | SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1 |
バックグラウンド: | The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | SLC19A1: a transporter protein. Transports reduced folate, antitumor agents and folate antagonists such as methotrexate. Apparently involved in methotrexate resistance in various cancers and neural tube defects. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: apical plasma membrane; basolateral plasma membrane; plasma membrane Molecular Function:folic acid binding; folic acid transporter activity; methotrexate transporter activity; reduced folate carrier activity Biological Process: folic acid metabolic process; folic acid transport; methotrexate transport |
NCBI Summary: | The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] |
UniProt Code: | P41440 |
NCBI GenInfo Identifier: | 12643280 |
NCBI Gene ID: | 6573 |
NCBI Accession: | P41440.3 |
UniProt Secondary Accession: | P41440,O00553, O60227, Q13026, Q9BTX8, B2R7U8, B7Z8C3 E9PFY4, |
UniProt Related Accession: | P41440 |
Molecular Weight: | Calculated MW: 54kDa/60kDa/64kDaObserved MW: 65kDa |
NCBI Full Name: | Folate transporter 1 |
NCBI Synonym Full Names: | solute carrier family 19 member 1 |
NCBI Official Symbol: | SLC19A1 |
NCBI Official Synonym Symbols: | CHMD; FOLT; IFC1; REFC; RFC1 |
NCBI Protein Information: | folate transporter 1 |
UniProt Protein Name: | Folate transporter 1 |
UniProt Synonym Protein Names: | Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; Solute carrier family 19 member 1 |
UniProt Gene Name: | SLC19A1 |
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