Anti-SLC16A7 Antibody (CAB3015)
- SKU:
- CAB3015
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SLC16A7 Antibody |
抗体コード: | CAB3015 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human SLC16A7 (NP_001257551.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | DU145, HepG2, HL-60, 293T, rat brain |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human SLC16A7 (NP_001257551.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TGEY KYMY MSCG AIVV AASV WLLI GNAI NYRL LAKE RKEE NARQ KTRE SEPL SKSK HSED VNVK VSNA QSVT SERE TNI |
遺伝子ID: | 9194 |
Uniprot: | O60669 |
セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
計算された分子量: | 52kDa |
観察された分子量: | 52kDa |
同義語: | SLC16A7, MCT2 |
バックグラウンド: | This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | SLC16A7: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 12q13 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:pyruvate secondary active transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity; pyruvate transmembrane transporter activity Biological Process: transmembrane transport |
NCBI Summary: | This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
UniProt Code: | O60669 |
NCBI GenInfo Identifier: | 313104141 |
NCBI Gene ID: | 9194 |
NCBI Accession: | O60669.2 |
UniProt Related Accession: | O60669 |
Molecular Weight: | |
NCBI Full Name: | Monocarboxylate transporter 2 |
NCBI Synonym Full Names: | solute carrier family 16 member 7 |
NCBI Official Symbol: | SLC16A7 |
NCBI Official Synonym Symbols: | MCT2 |
NCBI Protein Information: | monocarboxylate transporter 2 |
UniProt Protein Name: | Monocarboxylate transporter 2 |
UniProt Synonym Protein Names: | Solute carrier family 16 member 7 |
Protein Family: | Molybdate transporter |
UniProt Gene Name: | SLC16A7 |
UniProt Entry Name: | MOT2_HUMAN |
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