Anti-SENP8 Antibody (CAB12753)
- SKU:
- CAB12753
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-SENP8 Antibody |
抗体コード: | CAB12753 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human SENP8 (NP_660205.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Rat |
ポジティブサンプル: | 293T, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human SENP8 (NP_660205.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDPV VLSY MDSL LRQS DVSL LDPP SWLN DHII GFAF EYFA NSQF HDCS DHVS FISP EVTQ FIKC TSNP AEIA MFLE PLDL PNKR VVFL AIND NSNQ AAGG THWS LLVY LQDK NSFF HYDS HSRS NSVH AKQV AEKL EAFL GRKG DKLA FVEE KAPA QQNS YDCG MYVI CNTE ALCQ NFFR QQTE SLLQ LLTP AYIT KKRG EWKD LITT LAKK |
遺伝子ID: | 123228 |
Uniprot: | Q96LD8 |
セルラーロケーション: | |
計算された分子量: | 24kDa |
観察された分子量: | 24kDa |
同義語: | SENP8, DEN1, NEDP1, PRSC2 |
バックグラウンド: | This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants. |
UniProt Protein Function: | SENP8: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. Belongs to the peptidase C48 family. |
UniProt Protein Details: | Protein type:EC 3.4.22.68; Protease Chromosomal Location of Human Ortholog: 15q23 Cellular Component: cytosol; nucleus Molecular Function:endopeptidase activity; NEDD8-specific protease activity; SUMO-specific protease activity Biological Process: protein desumoylation; protein deubiquitination |
NCBI Summary: | This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
UniProt Code: | Q96LD8 |
NCBI GenInfo Identifier: | 26006881 |
NCBI Gene ID: | 123228 |
NCBI Accession: | Q96LD8.1 |
UniProt Secondary Accession: | Q96LD8,Q96QA4, |
UniProt Related Accession: | Q96LD8 |
Molecular Weight: | 24kDa |
NCBI Full Name: | Sentrin-specific protease 8 |
NCBI Synonym Full Names: | SUMO/sentrin peptidase family member, NEDD8 specific |
NCBI Official Symbol: | SENP8 |
NCBI Official Synonym Symbols: | DEN1; NEDP1; PRSC2 |
NCBI Protein Information: | sentrin-specific protease 8 |
UniProt Protein Name: | Sentrin-specific protease 8 |
UniProt Synonym Protein Names: | Deneddylase-1; NEDD8-specific protease 1; Protease, cysteine 2; Sentrin/SUMO-specific protease SENP8 |
Protein Family: | Sentrin-specific protease |
UniProt Gene Name: | SENP8 |
View AllClose