Anti-SCD5 Antibody (CAB13127)
- SKU:
- CAB13127
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SCD5 Antibody |
抗体コード: | CAB13127 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human SCD5 (NP_001032671.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | U-87MG, 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human SCD5 (NP_001032671.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MPGP ATDA GKIP FCDA KEEI RAGL ESSE GGGG PERP GARG QRQN IVWR NVVL MSLL HLGA VYSL VLIP KAKP LTL |
遺伝子ID: | 79966 |
Uniprot: | Q86SK9 |
セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
計算された分子量: | 28kDa/37kDa |
観察された分子量: | 38kDa |
同義語: | SCD5, ACOD4, FADS4, HSCD5, SCD2, SCD4 |
バックグラウンド: |
UniProt Protein Function: | SCD5: Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position. Belongs to the fatty acid desaturase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, multi-pass; Membrane protein, integral; EC 1.14.19.1; Oxidoreductase Chromosomal Location of Human Ortholog: 4q21.22 Cellular Component: endoplasmic reticulum membrane Molecular Function:oxidoreductase activity; stearoyl-CoA 9-desaturase activity Biological Process: unsaturated fatty acid biosynthetic process |
NCBI Summary: | Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q86SK9 |
NCBI GenInfo Identifier: | 162416247 |
NCBI Gene ID: | 79966 |
NCBI Accession: | Q86SK9.2 |
UniProt Secondary Accession: | Q86SK9,Q4W5Q5, Q8NDS0, Q9H7D1, B2RPG0, |
UniProt Related Accession: | Q86SK9 |
Molecular Weight: | 28,983 Da |
NCBI Full Name: | Stearoyl-CoA desaturase 5 |
NCBI Synonym Full Names: | stearoyl-CoA desaturase 5 |
NCBI Official Symbol: | SCD5 |
NCBI Official Synonym Symbols: | SCD2; SCD4; ACOD4; FADS4; HSCD5 |
NCBI Protein Information: | stearoyl-CoA desaturase 5 |
UniProt Protein Name: | Stearoyl-CoA desaturase 5 |
UniProt Synonym Protein Names: | Acyl-CoA-desaturase 4; HSCD5 |
Protein Family: | Stearoyl-CoA desaturase |
UniProt Gene Name: | SCD5 |
UniProt Entry Name: | SCD5_HUMAN |
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