Anti-SAM68 Antibody (CAB3886)
- SKU:
- CAB3886
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Description
抗体名: | Anti-SAM68 Antibody |
抗体コード: | CAB3886 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human SAM68 |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, HepG2, NIH/3T3, Jurkat, Rat testis |
免疫原: | A synthesized peptide derived from human SAM68 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 10657 |
Uniprot: | Q07666 |
セルラーロケーション: | |
計算された分子量: | 68 kDa |
観察された分子量: | 68KDa |
同義語: | Sam68, p62, p68 |
バックグラウンド: | This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
UniProt Protein Function: | KHDRBS1: a nuclear RNA-binding protein. May be involved in slicing and mRNA transport. Associates with src in mitosis. Binds to RNA via a heteronuclear ribonucleoprotein K homology domain. Exerts functionally separable effects on cell proliferation and survival, dependent on its ability to bind specifically to RNA. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 1p32 Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus Molecular Function:identical protein binding; protein binding; SH3/SH2 adaptor activity; DNA binding; RNA binding; protein complex binding; poly(U) binding; SH3 domain binding; poly(A) binding Biological Process: transcription, DNA-dependent; positive regulation of signal transduction; positive regulation of RNA export from nucleus; regulation of protein stability; signal transduction; positive regulation of translational initiation; cell proliferation; cell surface receptor linked signal transduction; regulation of RNA export from nucleus; mRNA processing; cell cycle arrest; G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent |
NCBI Summary: | This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q07666 |
NCBI GenInfo Identifier: | 62511098 |
NCBI Gene ID: | 10657 |
NCBI Accession: | Q07666.1 |
UniProt Related Accession: | Q07666 |
Molecular Weight: | ~ 48kDa |
NCBI Full Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
NCBI Synonym Full Names: | KH RNA binding domain containing, signal transduction associated 1 |
NCBI Official Symbol: | KHDRBS1 |
NCBI Official Synonym Symbols: | p62; p68; Sam68 |
NCBI Protein Information: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
UniProt Protein Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
UniProt Synonym Protein Names: | GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68 |
UniProt Gene Name: | KHDRBS1 |
UniProt Entry Name: | KHDR1_HUMAN |