Anti-SAFB2 Antibody (CAB4330)
- SKU:
- CAB4330
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SAFB2 Antibody |
抗体コード: | CAB4330 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SAFB2 (NP_055464.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, Jurkat, Mouse liver, Mouse pancreas |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SAFB2 (NP_055464.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAET LPGS GDSG PGTA SLGP GVAE TGTR RLSE LRVI DLRA ELKK RNLD TGGN KSVL MERL KKAV KEEG QDPD EIGI ELEA TSKK SAKR CVKG LKME EEGT EDNG LEDD SRDG QEDM EASL ENLQ NMGM MDMS VLDE TEVA NSSA PDFG EDGT DGLL DSFC DSKE YVAA QLRQ LPAQ PPEH AVDG EGFK NTLE TSSL NFKV TPDI EESL LEPE NEKI LDIL GETC KSEP VKEE SSEL EQPF AQDT SSVG PDRK LAE |
遺伝子ID: | 9667 |
Uniprot: | Q14151 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 12kDa/107kDa |
観察された分子量: | 160kDa |
同義語: | SAFB2 |
バックグラウンド: | The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. |
UniProt Protein Function: | SAFB2: Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; RNA-binding Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm Molecular Function:identical protein binding; protein binding; DNA binding; nucleotide binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
UniProt Code: | Q14151 |
NCBI GenInfo Identifier: | 38372432 |
NCBI Gene ID: | 9667 |
NCBI Accession: | Q14151.1 |
UniProt Secondary Accession: | Q14151,Q8TB13, B4DKG3, |
UniProt Related Accession: | Q14151 |
Molecular Weight: | 953 |
NCBI Full Name: | Scaffold attachment factor B2 |
NCBI Synonym Full Names: | scaffold attachment factor B2 |
NCBI Official Symbol: | SAFB2 |
NCBI Protein Information: | scaffold attachment factor B2; SAF-B2 |
UniProt Protein Name: | Scaffold attachment factor B2 |
Protein Family: | Scaffold attachment factor |
UniProt Gene Name: | SAFB2 |
UniProt Entry Name: | SAFB2_HUMAN |
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