Anti-RPL17 Antibody (CAB5934)
- SKU:
- CAB5934
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-RPL17 Antibody |
抗体コード: | CAB5934 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human RPL17 (NP_000976.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, 293T, A-549, SW480, HeLa, Mouse lung, Mouse thymus, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human RPL17 (NP_000976.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MVRY SLDP ENPT KSCK SRGS NLRV HFKN TRET AQAI KGMH IRKA TKYL KDVT LQKQ CVPF RRYN GGVG RCAQ AKQW GWTQ GRWP KKSA EFLL HMLK NAES NAEL KGLD VDSL VIEH IQVN KAPK MRRR TYRA HGRI NPYM SSPC HIEM ILTE KEQI VPKP EEEV AQKK KISQ KKLK KQKL MARE |
遺伝子ID: | 6139 |
Uniprot: | P18621 |
セルラーロケーション: | |
計算された分子量: | 17kDa/21kDa/26kDa |
観察された分子量: | 21kDa |
同義語: | RPL17, L17, PD-1, RPL23 |
バックグラウンド: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. |
UniProt Protein Function: | RPL17: a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010] |
UniProt Protein Details: | Protein type:Translation; Ribosomal Chromosomal Location of Human Ortholog: 18q21 Cellular Component: nucleus; cytosol Molecular Function:structural constituent of ribosome Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; gene expression; viral transcription; viral infectious cycle; translational termination |
NCBI Summary: | This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded isoforms share sequence identity with the RPL17 protein, but they include frameshifted C-terminal regions derived from the downstream gene exons. [provided by RefSeq, Dec 2010] |
UniProt Code: | P18621 |
NCBI GenInfo Identifier: | 132799 |
NCBI Gene ID: | 100526842 |
NCBI Accession: | P18621.3 |
UniProt Secondary Accession: | P18621,Q3KQW2, Q6NZ54, Q7M4M5, B2R4H3, B4E3C2, B5ME31 J3QL51, |
Molecular Weight: | 184 |
NCBI Full Name: | 60S ribosomal protein L17 |
NCBI Synonym Full Names: | RPL17-C18orf32 readthrough |
NCBI Official Symbol: | RPL17-C18orf32 |
NCBI Protein Information: | RPL17-C18orf32 protein |
UniProt Protein Name: | 60S ribosomal protein L17 |
UniProt Synonym Protein Names: | 60S ribosomal protein L23; PD-1 |
Protein Family: | 60S ribosomal protein |
UniProt Gene Name: | RPL17 |
UniProt Entry Name: | RL17_HUMAN |
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