Anti-RNF123 Antibody (CAB7618)
- SKU:
- CAB7618
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-RNF123 Antibody |
抗体コード: | CAB7618 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human RNF123 |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: |
免疫原: | Recombinant protein of human RNF123 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 63891 |
Uniprot: | Q5XPI4 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 148kDa |
観察された分子量: | Refer to figures |
同義語: | RNF123, FP1477, KPC1 |
バックグラウンド: | The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. |
NCBI Summary: | The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
UniProt Code: | Q5XPI4 |
NCBI GenInfo Identifier: | 37588869 |
NCBI Gene ID: | 63891 |
NCBI Accession: | NP_071347.2 |
UniProt Secondary Accession: | Q5XPI4,Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8 Q9H9T2, A1L4Q3, A6NLS5, |
UniProt Related Accession: | Q5XPI4 |
Molecular Weight: | 144 |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF123 |
NCBI Synonym Full Names: | ring finger protein 123 |
NCBI Official Symbol: | RNF123 |
NCBI Official Synonym Symbols: | KPC1; FP1477 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF123 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF123 |
UniProt Synonym Protein Names: | Kip1 ubiquitination-promoting complex protein 1; RING finger protein 123; RING-type E3 ubiquitin transferase RNF123Curated |
UniProt Gene Name: | RNF123 |
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