Anti-RMI2 Antibody (CAB8523)
- SKU:
- CAB8523
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-RMI2 Antibody |
抗体コード: | CAB8523 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human RMI2 (NP_689521.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa, MCF7 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human RMI2 (NP_689521.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAA ADSF SGGP AGVR LPRS PPLK VLAE QLRR DAEG GPGA WRLS RAAA GRGP LDLA AVWM QGRV VMAD RGEA RLRD PSGD FSVR GLER VPRG RPCL VPGK YVMV MGVV QACS PEPC LQAV KMTD LSDN PIHE SMWE LEVE DLHR NIP |
遺伝子ID: | 116028 |
Uniprot: | Q96E14 |
セルラーロケーション: | Nucleus |
計算された分子量: | 9kDa/15kDa |
観察された分子量: | 16kDa |
同義語: | RMI2, BLAP18, C16orf75 |
バックグラウンド: |
UniProt Protein Function: | Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM. |
NCBI Summary: | RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008] |
UniProt Code: | Q96E14 |
NCBI GenInfo Identifier: | 24308245 |
NCBI Gene ID: | 116028 |
NCBI Accession: | NP_689521.1 |
UniProt Secondary Accession: | Q96E14,Q49AE2, Q8TBL0, B3KVZ6, |
UniProt Related Accession: | Q96E14 |
Molecular Weight: | 9,262 Da |
NCBI Full Name: | recQ-mediated genome instability protein 2 |
NCBI Synonym Full Names: | RecQ mediated genome instability 2 |
NCBI Official Symbol: | RMI2 |
NCBI Official Synonym Symbols: | BLAP18; C16orf75 |
NCBI Protein Information: | recQ-mediated genome instability protein 2 |
UniProt Protein Name: | RecQ-mediated genome instability protein 2 |
UniProt Synonym Protein Names: | BLM-associated protein of 18 kDa; BLAP18 |
Protein Family: | RecQ-mediated genome instability protein |
UniProt Gene Name: | RMI2 |
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