Anti-RHD Antibody (CAB15092)
- SKU:
- CAB15092
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
抗体名: | Anti-RHD Antibody |
抗体コード: | CAB15092 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human RHD (NP_001121163.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | mouse liver, rat liver |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human RHD (NP_001121163.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LGNL RMVI SNIF NTDY HMNM MHIY VFAA YFGL SVAW CLPK PLPE GTED KDQT ATIP SLSA MLGA LFLW MFWP SFNS ALLR SPIE RKNA VFNT YYAV AVSV V |
遺伝子ID: | 6007 |
Uniprot: | Q02161 |
セルラーロケーション: | Membrane, Multi-pass membrane protein |
計算された分子量: | 34kDa/41kDa/43kDa/45kDa/53kDa |
観察された分子量: | 36kDa |
同義語: | RHD, CD240D, DIIIc, RH, RH30, RHCED, RHDVA(TT), RHDel, RHPII, RHXIII, Rh4, RhDCw, RhII, RhK562-II, RhPI |
バックグラウンド: | The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | RHD: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: integral to plasma membrane Molecular Function:ammonium transmembrane transporter activity Biological Process: nitrogen utilization; organic cation transport |
NCBI Summary: | The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02161 |
NCBI GenInfo Identifier: | 296452980 |
NCBI Gene ID: | 6007 |
NCBI Accession: | Q02161.3 |
UniProt Secondary Accession: | Q02161,Q02162, Q07618, Q16147, Q16235, Q16355, Q5VSK0 Q5XLS9, Q5XLT1, Q5XLT2, Q9NPK0, Q9UQ20, |
UniProt Related Accession: | Q02161 |
Molecular Weight: | 41,694 Da |
NCBI Full Name: | Blood group Rh(D) polypeptide |
NCBI Synonym Full Names: | Rh blood group D antigen |
NCBI Official Symbol: | RHD |
NCBI Official Synonym Symbols: | RH; Rh4; RH30; RhII; RhPI; DIIIc; RHCED; RHDel; RHPII; RhDCw; CD240D; RHXIII; RHDVA(TT); RhK562-II |
NCBI Protein Information: | blood group Rh(D) polypeptide |
UniProt Protein Name: | Blood group Rh(D) polypeptide |
UniProt Synonym Protein Names: | RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD_antigen: CD240D |
UniProt Gene Name: | RHD |
UniProt Entry Name: | RHD_HUMAN |
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