Anti-RBM39 Antibody (CAB15760)
- SKU:
- CAB15760
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-RBM39 Antibody |
抗体コード: | CAB15760 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human RBM39 (NP_001229528.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BxPC-3, U-251MG, 293T, LO2, Mouse brain, Mouse heart |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human RBM39 (NP_001229528.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ATQC FQLS NMFN PQTE EEVG WDTE IKDD VIEE CNKH GGVI HIYV DKNS AQGN VYVK CPSI AAAI AAVN ALHG RWFA GKMI TAAY VPLP TYHN LFPD SMTA TQLL VPSR R |
遺伝子ID: | 9584 |
Uniprot: | Q14498 |
セルラーロケーション: | Nucleus speckle |
計算された分子量: | 57kDa/58kDa/59kDa |
観察された分子量: | 70kDa |
同義語: | RBM39, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2 |
バックグラウンド: | This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. |
UniProt Protein Function: | RNPC2: Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1. May be involved in pre-mRNA splicing process. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Nuclear receptor co-regulator; Spliceosome Chromosomal Location of Human Ortholog: 20q11.22 Cellular Component: nucleoplasm; microtubule cytoskeleton; microtubule organizing center; nuclear speck Molecular Function:protein binding; nucleotide binding Biological Process: RNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA splicing; mRNA processing |
NCBI Summary: | This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011] |
UniProt Code: | Q14498 |
NCBI GenInfo Identifier: | 28201880 |
NCBI Gene ID: | 9584 |
NCBI Accession: | Q14498.2 |
UniProt Secondary Accession: | Q14498,Q14499, A2RRD3, A5D8W2, B0BLV3, E1P5S0, E1P5S1 |
UniProt Related Accession: | Q14498 |
Molecular Weight: | 530 |
NCBI Full Name: | RNA-binding protein 39 |
NCBI Synonym Full Names: | RNA binding motif protein 39 |
NCBI Official Symbol: | RBM39 |
NCBI Official Synonym Symbols: | HCC1; CAPER; RNPC2; FSAP59; CAPERalpha |
NCBI Protein Information: | RNA-binding protein 39; CAPER alpha; splicing factor HCC1; hepatocellular carcinoma protein 1; RNA-binding region (RNP1, RRM) containing 2; functional spliceosome-associated protein 59; coactivator of activating protein-1 and estrogen receptors |
UniProt Protein Name: | RNA-binding protein 39 |
UniProt Synonym Protein Names: | CAPER alpha; Hepatocellular carcinoma protein 1; RNA-binding motif protein 39; RNA-binding region-containing protein 2; Splicing factor HCC1 |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | RBM39 |
UniProt Entry Name: | RBM39_HUMAN |
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