Anti-RARRES3 Antibody (CAB8784)
- SKU:
- CAB8784
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-RARRES3 Antibody |
抗体コード: | CAB8784 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RARRES3 (NP_004576.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RARRES3 (NP_004576.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MASP HQEP KPGD LIEI FRLG YEHW ALYI GDGY VIHL APPS EYPG AGSS SVFS VLSN SAEV KRER LEDV VGGC CYRV NNSL DHEY QPRP VEVI ISSA KEMV GQKM KYSI VSRN CEHF VTQL RYGK SRCK QVEK AKV |
遺伝子ID: | 5920 |
Uniprot: | Q9UL19 |
セルラーロケーション: | Membrane, Single-pass membrane protein |
計算された分子量: | 17kDa/18kDa |
観察された分子量: | 18kDa |
同義語: | RARRES3, HRASLS4, HRSL4, PLA1/2-3, RIG1, TIG3 |
バックグラウンド: | Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. |
UniProt Protein Function: | RARRES3: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable. Belongs to the H-rev107 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation; EC 3.1.1.- Chromosomal Location of Human Ortholog: 11q23 Molecular Function:phospholipase A2 activity; protein binding Biological Process: phospholipid metabolic process |
NCBI Summary: | Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UL19 |
NCBI GenInfo Identifier: | 20140910 |
NCBI Gene ID: | 5920 |
NCBI Accession: | Q9UL19.1 |
UniProt Secondary Accession: | Q9UL19,O95200, B2R599, B4DDW2, E7ENZ7, |
UniProt Related Accession: | Q9UL19 |
Molecular Weight: | 17,436 Da |
NCBI Full Name: | Retinoic acid receptor responder protein 3 |
NCBI Synonym Full Names: | retinoic acid receptor responder 3 |
NCBI Official Symbol: | RARRES3 |
NCBI Official Synonym Symbols: | RIG1; TIG3; HRSL4; HRASLS4; PLA1/2-3 |
NCBI Protein Information: | retinoic acid receptor responder protein 3 |
UniProt Protein Name: | Retinoic acid receptor responder protein 3 |
UniProt Synonym Protein Names: | HRAS-like suppressor 4; HRSL4; RAR-responsive protein TIG3; Retinoid-inducible gene 1 protein; Tazarotene-induced gene 3 protein |
Protein Family: | Retinoic acid receptor responder protein |
UniProt Gene Name: | RARRES3 |
UniProt Entry Name: | HRSL4_HUMAN |
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