Anti-PTGR1 Antibody (CAB4521)

(No reviews yet) Write a Review
SKU:
CAB4521
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PTGR1
Synonyms:
LTB4DH
Synonyms:
PGR1
Synonyms:
ZADH3
€0.00
Frequently bought together:

Description

抗体名:PTGR1 Rabbit pAb
抗体コード:CAB4521
サイズ:20uL, 50uL, 100uL
同義語:PTGR1, LTB4DH, PGR1, ZADH3
申し込み:WB
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human PTGR1 (NP_036344.2).
申し込み:WB
推奨される希釈:WB 1:500 - 1:2000
反応性:Human, Mouse
ポジティブサンプル:HeLa, Mouse heart, Mouse kidney
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human PTGR1 (NP_036344.2).
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MVRT KTWT LKKH FVGY PTNS DFEL KTAE LPPL KNGE VLLE ALFL TVDP YMRV AAKR LKEG DTMM GQQV AKVV ESKN VALP KGTI VLAS PGWT THSI SDGK DLEK LLTE WPDT IPL
遺伝子ID:22949
Uniprot:Q14914
セルラーロケーション:Cytoplasm
計算された分子量:32kDa/35kDa
観察された分子量:36kDa
UniProt Protein Function:LTB4DH: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. Belongs to the NADP-dependent oxidoreductase L4BD family.
UniProt Protein Details:

Protein type:EC 1.3.1.48; Oxidoreductase; EC 1.3.1.74

Chromosomal Location of Human Ortholog: 9q31.3

Cellular Component: cytoplasm

Molecular Function:15-oxoprostaglandin 13-oxidase activity; zinc ion binding; 2-alkenal reductase activity

Biological Process: response to toxin; cyclooxygenase pathway; arachidonic acid metabolic process; leukotriene metabolic process

NCBI Summary:This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
UniProt Code:Q14914
NCBI GenInfo Identifier:23503081
NCBI Gene ID:22949
NCBI Accession:Q14914.2
UniProt Secondary Accession:Q14914,Q8IYQ0, Q9H1X6, A8K0N2, B4DPK3, F5GY50,
UniProt Related Accession:Q14914
Molecular Weight:329
NCBI Full Name:Prostaglandin reductase 1
NCBI Synonym Full Names:prostaglandin reductase 1
NCBI Official Symbol:PTGR1  
NCBI Official Synonym Symbols:PGR1; ZADH3; LTB4DH  
NCBI Protein Information:prostaglandin reductase 1; PRG-1; 15-oxoprostaglandin 13-reductase; leukotriene B4 12-hydroxydehydrogenase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; zinc binding alcohol dehydrogenase domain containing 3
UniProt Protein Name:Prostaglandin reductase 1
UniProt Synonym Protein Names:15-oxoprostaglandin 13-reductase (EC:1.3.1.48); NADP-dependent leukotriene B4 12-hydroxydehydrogenase (EC:1.3.1.74)
Protein Family:Prostaglandin reductase
UniProt Gene Name:PTGR1  
UniProt Entry Name:PTGR1_HUMAN
View AllClose

View AllClose

Related Products